This work examines modern pharmaceutical compacting techniques used to form tablets from powders. It describes the physical structure of pharmaceutical compacts, the bonding phenomena that occur during powder compaction, and the compression mechanisms of pharmaceutical particles. Fundamental theories of compaction are covered; questions of dominating bond types are investigated; and the bonding area between particles in pharmaceutical compacts is analyzed.
Edited by:
Goran Alderborn,
Christer Nystrom
Imprint: CRC Press Inc
Country of Publication: United States
Volume: v. 71
Dimensions:
Height: 229mm,
Width: 152mm,
Spine: 34mm
Weight: 1.330kg
ISBN: 9780824793760
ISBN 10: 0824793765
Pages: 1014
Publication Date: 26 September 1995
Audience:
College/higher education
,
Professional and scholarly
,
Further / Higher Education
,
Undergraduate
Format: Hardback
Publisher's Status: Active
Interparticulate Bonding Characteristics of Pharmaceutical Compacts Interparticulate Attraction Mechanisms, Claus Führer The Importance of Intermolecular Bonding Forces and the Concept of Bonding Surface Area, Christer Nyström and Per-Gunnar Karehill Characterization of the Compression Process Porosity-Pressure Functions, Petteri Paronen and Jukka Ilkka Force-Displacement and Network Measurements, Gert Ragnarsson Viscoelastic Models, Fritz Müller Application of Percolation Theory and Fractal Geometry to Tablet Compaction, Hans Leuenberger, Ruth Leu, and Jean-Daniel Bonny Characterization of Compact Properties Mechanical Strength, Peter N. Davies and J. Michael Newton Tablet Surface Area, N. Anthony Armstrong Rationale for and the Measurement of Tableting Indices, Everett N. Hiestand Material Properties of Importance for Powder Volume Reduction and Compact Strength Particle Dimensions, Göran Alderborn Mechanical Properties, Ray C. Rowe and Ron J. Roberts Granule Properties, Göran Alderborn and Martin Wikberg Modeling the Compression Behavior of Particle Assemblies from the Mechanical Properties of Individual Particles, Wendy C. Duncan-Hewitt Compaction Properties of Excipients and Powder Mixtures Materials for Direct Compaction, Gerald K. Bolhuis and Zak T. Chowhan Compaction Properties of Binary Mixtures, John T. Fell Lubricant Sensitivity, Gerad K. Bolhuis and Arne W. Hölzer The Development and Optimization of Tablet Formulations Using Mathematical Methods, Fridrun Podczeck
Göran Alderborn, Christer Nyström
Reviews for Pharmaceutical Powder ComPattion Technology
This volume attains excellent quality in presenting updated information. -American Journal of Pharmaceutical Education extremely valuable in any library associated with tablet formulation. -Journal of Controlled Release
