Organozinc reagents are less reactive than Grignard reagents but they are much more chemoselective. Since the Negishi cross-coupling reaction developed by Ei-ichi Negishi, who was awarded the Nobel Price in chemistry in 2010, a number of cross-coupling reactions involving organozinc derivatives and transition metal catalysts (Pd, Ni, Fe, Co, Cu, …) has been tuned up to form C-C bonds. This book on ""Organozinc derivatives and transition metal catalysts"" has been written by experts in the field and is a complement to the book entitled ""Grignard reagents and transition metal catalysts"" (a De Gruyter book, edited by J. Cossy).
Grignard reagents or organozinc reagents, that is the question? From a given substrate, what is the best organometallic reagent and the best transition metal to form a C-C bond by using a cross-coupling reaction? The solution might be found in these two books.
Edited by:
Janine Cossy Imprint: De Gruyter Country of Publication: Germany Dimensions:
Height: 240mm,
Width: 170mm,
Weight: 505g ISBN:9783110728774 ISBN 10: 311072877X Pages: 222 Publication Date:22 May 2023 Audience:
Professional and scholarly
,
Undergraduate
Format:Hardback Publisher's Status: Active
Janine Cossy is Professor of Organic Chemistry at the ESPCI Paris since 1990. Her research interests focus on the synthesis of natural products and/or biologically active compounds as well as on the development of synthetic methods.