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Organozinc Derivatives and Transition Metal Catalysts

Formation of C-C Bonds by Cross-coupling

Janine Cossy

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Hardback

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English
De Gruyter
22 May 2023
Organozinc reagents are less reactive than Grignard reagents but they are much more chemoselective. Since the Negishi cross-coupling reaction developed by Ei-ichi Negishi, who was awarded the Nobel Price in chemistry in 2010, a number of cross-coupling reactions involving organozinc derivatives and transition metal catalysts (Pd, Ni, Fe, Co, Cu, …) has been tuned up to form C-C bonds. This book on ""Organozinc derivatives and transition metal catalysts"" has been written by experts in the field and is a complement to the book entitled ""Grignard reagents and transition metal catalysts"" (a De Gruyter book, edited by J. Cossy).

Grignard reagents or organozinc reagents, that is the question? From a given substrate, what is the best organometallic reagent and the best transition metal to form a C-C bond by using a cross-coupling reaction? The solution might be found in these two books.
Edited by:  
Imprint:   De Gruyter
Country of Publication:   Germany
Dimensions:   Height: 240mm,  Width: 170mm, 
Weight:   505g
ISBN:   9783110728774
ISBN 10:   311072877X
Pages:   222
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Hardback
Publisher's Status:   Active

Janine Cossy is Professor of Organic Chemistry at the ESPCI Paris since 1990. Her research interests focus on the synthesis of natural products and/or biologically active compounds as well as on the development of synthetic methods.

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