The field of oral microbiology has seen fundamental conceptual changes in recent years. Microbial communities are now seen as the fundamental etiological agent in oral diseases through their interface with host inflammatory responses. Study of structured microbial communities has increased our understanding of the roles of each member in the pathogenesis of oral diseases, principles that apply to both periodontitis and dental caries.
Against this backdrop, the third edition of Oral Microbiology and Immunology has been substantially expanded and rewritten by an international team of authors and editors. Featured in the current edition are:
links between oral infections and systemic disease revised and updated overview of the role of the immune system in oral infections thorough discussions of biofilm development and control more extensive illustrations and Key Points for student understanding
Graduate students, researchers, and clinicians as well as students will find this new edition valuable in study and practice. The field of oral microbiology has seen fundamental conceptual changes in recent years. Microbial communities are now seen as the fundamental etiological agent in oral diseases through their interface with host inflammatory responses. Study of structured microbial communities has increased our understanding of the roles of each member in the pathogenesis of oral diseases, principles that apply to both periodontitis and dental caries.
Contributors xxi Preface xxv About the Editors xxvii Section I General Principles of Oral Microbiology and Immunology 1 1 General Microbiology 3 Howard F. Jenkinson Key points 28 2 The Immune System and Its Functions 29 George Hajishengallis and Jonathan M. Korostoff Key points 50 Further Reading 51 3 The Oral Environment 53 Frank A. Scannapieco and Stefan Ruhl Key points 80 Further Reading 80 4 Isolation, Classification, and Identification of Oral Bacteria 81 Eugene J. Leys, Ann L. Griffen, and Clifford Beall Key points 99 Further Reading 99 5 Oral Microbial Ecology 101 Howard F. Jenkinson and Richard J. Lamont Key points 121 Further Reading 122 6 Oral Microbial Physiology 123 Paul G. Egland and Robert E. Marquis Key points 147 Further Reading 147 7 Genetics and Molecular Biology of Oral Microorganisms 149 Angela H. Nobbs, Bing-Yan Wang, and Gena D. Tribble Key points 187 Further Reading 188 8 Applied Molecular Biology and the Oral Microbes 189 Hansel M. Fletcher, Arunima Mishra, Sasanka Chukkapalli, Stuart Dashper, and Ann Progulske-Fox Key points 211 Further Reading 212 9 Population Genetics of Oral Bacteria 213 Mogens Kilian Key points 225 Further Reading 226 10 Immunology of the Oral Cavity 227 Evlambia Hajishengallis and George Hajishengallis Key points 248 Further Reading 248 Section II Infection-Driven Oral Diseases 249 11 Dental Caries: Etiology and Pathogenesis 251 William H. Bowen, Livia M. A. Tenuta, Hyun Koo, and Jaime A. Cury Key points 265 Further Reading 265 12 Pathogenic Mechanisms in Dental Caries 267 José A. Lemos, Hui Wu, Robert G. Quivey, Jr., and Hyun Koo Key points 284 Further Reading 285 13 Periodontal Diseases: General Concepts 287 Panos N. Papapanou Key points 307 Further Reading 307 14 Virulence Factors of Periodontal Bacteria 309 Richard J. Lamont, Janina P. Lewis, and Jan Potempa 15 Immunopathogenic Mechanisms in Periodontal Disease 333 George Hajishengallis Key points 356 Further Reading 357 16 Oral Virology 359 Matti Sällberg Key points 395 Further Reading 396 17. Fungi and Fungal Infections of the Oral Cavity 397 Richard D. Cannon, Ann R. Holmes, and Norman A. Firth Key points 414 Further Reading 415 18 Endodontic Infections and Therapeutic Approaches 417 Brenda P. F. A. Gomes, Isabela N. Rôças, and José F. Siqueira, Jr. Further Reading 432 19 Systemic Disease and the Oral Microbiota 433 Angela H. Nobbs and Mark C. Herzberg Section III Control of Oral Diseases 455 20 Antibiotics: Mechanisms of Action, Resistance, and Clinical Use in Dentistry 457 Pin-Chuang Lai, Hyun Koo, Paul Stoodley, and John Walters Key points 494 Further Reading 494 21 Therapeutic Approaches for Biofilm Control and Host Modulation in Oral Diseases 495 Yijin Ren, Henry C. van der Mei, George Hajishengallis, Hyun Koo, and Henk J. Busscher Key points 522 Further Reading 522 22 Infection Prevention and Control in Dentistry 525 J. Christopher Fenno, Stephen J. Stefanac, and Brandonn K. Perry Key points 549 Further Reading 550 Index 551
Howard F. Jenkinson, George N. Hajishengallis, Richard J. Lamont and Hyun koo
Reviews for Oral Microbiology and Immunology
The textbook is a great resource for undergraduate and graduate dental students, dental educators, and researchers alike. It builds upon principles of general microbiology and immunology and, through the scope of the oral cavity as a specialized niche of the human body, delves into the concepts of oral microbiology and oral immunology. These are further applied to provide a thorough understanding of the etiopathogenesis of oral microbial diseases, using both classical and contemporary literature. The textbook efficiently integrates research findings into education, for the establishment of knowledge. Georgios Belibasakis, DDS, MSc, PhD, FHEA, Professor of Clinical Oral Infection Biology, Karolinska Institutet Oral Microbiology and Immunology has been a valuable resource for instructors in oral health for years. The third edition is thoroughly updated with current technologies and research, from new findings on pathogenic organisms and oral diseases to practical safety approaches. I highly recommend the textbook to students, teachers and scientists involved in oral microbiology and immunology. Salomon Amar, DDS, PhD, Professor of Pharmacology and Microbiology and Immunology, New York Medical College, Valhalla
