Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cortical System

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Erwin B. Montgomery Jr., MD (Emeritus Professor, Department of Medicine (Neurology), McMaster University, Hamilton, ON, Canada) Olivier Darbin (Assistant Professor, Department of Neurosurgery, University of South Alabama, AL, United States)

Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cortical System

Erwin B. Montgomery Jr., MD (Emeritus Professor, Department of Medicine (Neurology), McMaster University, Hamilton, ON, Canada), Olivier Darbin (Assistant Professor, Department of Neurosurgery, University of South Alabama, AL, United States)

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English

Academic Press Inc
22 June 2023

Neurology & clinical neurophysiology; Neurosciences

Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cortical System examines current research regarding the operations of the basal ganglia-thalamic-cortical system that causes neurological disorders like Parkinson’s disease. While there have been remarkable advances in the understanding of the anatomy, physiology and chemistry of these systems, there remains a significant degree of inconsistency and incompleteness between facts and advancements. This book introduces the novel concepts of nonlinear complex systems and their connection to Parkinsonism as well as hyperkinetic disorders. The actual mechanisms underlying the motor disorders of Parkinson’s disease at the level of the lower motor neuron are also discussed.

By: Erwin B. Montgomery Jr. MD (Emeritus Professor Department of Medicine (Neurology) McMaster University Hamilton ON Canada), Olivier Darbin (Assistant Professor, Department of Neurosurgery, University of South Alabama, AL, United States)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 229mm, Width: 152mm,
Weight: 660g
ISBN: 9780443216992
ISBN 10: 0443216991
Pages: 404
Publication Date: 22 June 2023
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Dr. Montgomery has been an academic neurologist for over 40 years pursuing teaching, clinical and basic research at major academic medical centers. He has authored over 120 peer reviewed journal articles (available on PubMed) and 8 books on medicine (4 on the subject of Deep Brain Stimulation). The last two have been “Reproducibility in Biomedical Research (Academic Press, 2024) and “The Ethics of Everyday Medicine (Academic Press, 2023). Dr. Darbin pursues theoric, basic and translational research on the function of the basal ganglia and has worked at major centres in Europe, America and Japan. He has authored over 50 peer reviewed journal articles (available on PubMed) in biochemistry, neurophysiology and psychophysiology. His current research is on therapeutic on-demand for conditions with movement disorders (Nature Scientific Report, 2022).

Reviews for Nonlinear Dynamics of Parkinson’s Disease and the Basal Ganglia-Thalamic-Cortical System

""...describes the dynamics of basal ganglia networks... [and] theories that express the dynamic interaction between these functional nuclei... [including] thalamus and cortical interactions.... [A]pproaches the current therapeutic interventions and elaborates on the lack of clear theories that explain the current response to therapies.... [D]elves into detailed mathematical and physical analyses, which makes it well suited for researchers interested in medical sciences… [W]ritten with detailed discussion of theoretical analysis of interactions between different brain areas involved in movement, particularly Parkinson’s disease.... [A] good addition to the field of movement disorders. As the field is growing and interaction between complete logical machines is accomplished and understood (e.g., deep brain stimulation), the better automated this interaction can be achieved. This can be a game changer in deep brain stimulation for many patients to achieve a state-of-the-art automated therapy based on their symptoms."" — ©Doody’s Review Service, 2024, Karim Makhoul, MD (Northwell Health)