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Network Analysis of Mitochondrial Genome

Rahul Kumar Verma

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English
Mohammed Abdul Sattar
18 January 2024
"The identity of an individual entity lies in the wholeness of the system in which it is present. We observe numerous complex phenomena happening around us, and to study them, we define them as systems with particular entities leading to the commencement of those phenomena. Modelling these complex systems gives rise to the formation of complex networks. These networks represent the meaningful connections between the entities of the complex system. ""I think the next century (21st) will be the century of complexity"", once said Stephen Hawking in light of the omnipresence of complex systems around us. The past two decades observed the immense potential of network science due to its holistic approach, flexibility, and applications to vast fields of scientific research. Network science has provided various models and algorithms under the umbrella of statistical physics to analyze natural and social sciences, including complex biological systems. Like any other physical system, it is also required to identify and characterize the individual building blocks in complex biological systems and obtain and establish insights into the interactions.

The biological complex systems can be defined by multiple types of entities such as biomolecules (proteins and genes), pathways (metabolic, anabolic, and disease), cells (neurons), tissues (brain regions), and organs (human complexome) along with their defined interactions. In biological systems, interactions among cellular entities are not always straightforward as in social and physical networks. Hence, their interpretation becomes much more complicated, aided by the immense size, temporal dynamics, and non-linearity behaviour. However, the vast diversity of biological systems allows us to define them at various levels into network models."

By:  
Imprint:   Mohammed Abdul Sattar
Dimensions:   Height: 279mm,  Width: 216mm,  Spine: 5mm
Weight:   259g
ISBN:   9798224677177
Pages:   102
Publication Date:  
Audience:   General/trade ,  ELT Advanced
Format:   Paperback
Publisher's Status:   Active

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