Nanotechnology in Ophthalmology

Mahendra Rai, Marcelo Luis Occhiutto, MD, Sushama Talegaonkar

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English

Academic Press Inc
28 July 2023

Pharmaceutical industries; Pharmacology; Biomedical engineering; Life sciences: general issues; Biotechnology

Nanotechnology in Ophthalmology is a comprehensive and up-to-date reference on the role and applications of nanotechnology in ophthalmology, from drug delivery and treatment of ocular diseases to toxicity issues. Written by experts from the nanotechnology, ophthalmology, and pharmacology fields, this book has a unique, broad and diverse scope, including chapters on nanosensor-based diagnostic tools, delivery of nanobiomaterials, implantable materials and devices, delivery of nanobiomaterials, nanotechnology for medical and surgical treatment, regenerative medicine, and more. This book provides a valuable reference to researchers working in the areas of ophthalmology, nanoscience and pharmacology, and clinical fellows who are interested in nanoophthalmology as a reference for their practice and research.

Edited by: Mahendra Rai, Marcelo Luis Occhiutto, MD, Sushama Talegaonkar
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 235mm, Width: 191mm,
ISBN: 9780443152641
ISBN 10: 0443152640
Pages: 480
Publication Date: 28 July 2023
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Section I: Ocular diseases: an overview 1. Nanotechnology in ophthalmology: an overview 2. Ischemia and reperfusion in ocular tissues 3. Ocular pathophysiology in diabetes mellitus Section II: Perspectives of Nanotechnology in Ocular Drug Delivery 4. An overview of ocular drug delivery systems: conventional and novel drug delivery systems 5. Biopharmaceutical considerations and characterization techniques for the ophthalmic drug delivery therapeutics 6. Computational biology for the in-silico assessment of ocular drug delivery therapeutics Section III: Biomedical Applications of Nanocarriers in Ocular Diseases 7. Nano-ocular delivery of peptides 8. Nanotechnology for the treatment of allergic conjunctival diseases 9. An overview of nanocarriers used in corneal diseases 10. Nanomedicine-based solutions (nanoemulsion and nanosuspension) for ocular diseases 11. Nanotechnology for medical and surgical glaucoma treatment 12. Nanovesicular drug delivery systems in glaucoma 13. Polymeric and lipid nanocarriers in glaucoma 14. Lipid-based nanotherapeutic interventions for treatment of ocular diseases: current status and future perspectives 15. Ocular inflammation and nanotechnology 16. Nanotechnology in retinal drug delivery 17. Advances in nanotherapies in the management of microbial keratitis 18. Polymeric micelles in fungal keratitis 19. Use of nanotechnology in dry eye syndrome 20. Advances in nanotechnology-based anti-VEGF agents for the management of ocular angiogenesis. 21. Applied nanotechnology for oxidative stress induced ocular neurodegenerative diseases 22. Nanotechnology in age-related maculardegeneration (AMD) 23. Noninvasive delivery of therapeutics in diabetic retinopathy: a shift to safe and patient compliant approach 24. Nanotechnological strategies for the treatment of diabetic retinopathy: progress and limitations 25. Hydrogel based drug delivery system in ocular drug delivery Section IV: Patents, Toxicity, Safety Issues and Regulations 26. A patent perspective for nanoformulations for ocular drug delivery 27. Toxicity of nanomaterials

Professor Mahendra Rai is a UGC-Basic Science Research Faculty Fellow and former head of the Department of Biotechnology, Sant Gadge Baba Amravati University, India. Presently, he is a visiting Scientist at the Department of Microbiology, Nicolaus Copernicus University, Poland. He is a member of several scientific societies. His areas of expertise include microbial biotechnology and nanobiotechnology. Currently, his group’s main research interest is green synthesis of metal nanoparticles particularly using fungi and their applications as nanoantimicrobials against pathogenic microbes. Prof. Rai has received several prestigious awards, including the Medini Award by the Government of India. He has been featured in Stanford’s list of the top 2% of scientists in nanoscience. Marcelo Occhiutto, MD, is a Physician in the Department of Anterior Segment and Refractive Surgery of the Tadeu Cvintal Institute of Ophthalmology, Brazil. He is also a Researcher at the Department of Ophthalmology and Human Genetics in the University of Campinas. His most recent research focuses on the use of nanotechnology for antiproliferative drugs in glaucoma surgeries and the identification of genetic polymorphisms that participate in the etiology of this serious eye disease. Dr. Sushama Talegaonkar is an Associate Professor at the Department of Pharmaceutics, Delhi Pharmaceutical Sciences and Research University, India. She has approximately 21 years of experience, and has published more than 220 research papers in high impact international journals. Besides this, she has coauthored 6 books and authored 15 chapters in international reference books. Recently, she received the Professor C. J. Shishoo Award for Best Research. Her research paper titled “Development and bioavailability assessment of ramipril nanoemulsion formulation has received the most cited research paper award on behalf of Elsevier and the board of European Journal of Pharmaceutics and Biopharmaceutics. She was awarded the prestigious Motan Devi Dandiya Biennial Prize for best publication in Pharmaceutical Sciences for the period 2010–11. Dr. Talegaonkar is actively involved in developing a wide variety of smart and functionalized nanodrug delivery systems for targeted anticancer drug delivery.