Myelin Repair and Neuroprotection in Multiple Sclerosis

Name: Myelin Repair and Neuroprotection in Multiple Sclerosis
Price: 356.62 AUD
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ISBN: 9781461422174

Ian D. Duncan, Robin J M Franklin

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Hardback

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English

Springer-Verlag New York Inc.
31 August 2012

Cellular physiology; Neurology & clinical neurophysiology; Radiology; Neurosciences

Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research frontiers still exist in this challenging disease. The cause remains elusive, preventing breakthroughs in its prevention. The move towards oral immunomodulatory therapies has been a major advance, as has the finding of new genes linked to susceptibility that may open the door to new therapeutic approaches. However, a frontier that has been making significant strides in recent years has been that surrounding the neurobiology of myelin regeneration and axon protection: such have been the advances that clinical translation is on the cusp of being achieved. Two broad approaches to therapeutic enhancement of remyelination are envisaged: promoting endogenous remyelination by targeting cells present in the CNS, or, replacing lost myelinating cells from exogenous sources. Current research on oligodendrocyte biology, the pathology of MS, imaging of lesions and the biology of remyelination are paving the way toward opening this new translational frontier.

Professor Duncan and Professor Franklin have assembled a broad group of experts in the fields of glial cell biology, neuropathology, radiology and clinical neurology to provide the background toward taking remyelination from experimented models into MS patients.

Edited by: Ian D. Duncan, Robin J M Franklin
Imprint: Springer-Verlag New York Inc.
Country of Publication: United States
Edition: 2012
Dimensions: Height: 235mm, Width: 155mm, Spine: 23mm
Weight: 623g
ISBN: 9781461422174
ISBN 10: 1461422175
Pages: 290
Publication Date: 31 August 2012
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Reviews for Myelin Repair and Neuroprotection in Multiple Sclerosis

From the book reviews: The textbook discusses the cellular and molecular mediators of demyelination and regeneration of myelin support. It does a credible and well evidenced job at these two goals. National and international experts contribute to the dialogue. ... I recommend this book to neurologists, neuroscientists, neurosurgeons ... . (Joseph J. Grenier, Amazon.com, August, 2014)