The book is essential for those seeking to understand innovative and sustainable solutions to global food insecurity and health challenges, as it offers invaluable insights into the transformative potential of mushroom biotechnology and its applications.
The intervention of microbial biotechnology in various sectors has displayed remarkable growth linked to sustainable innovations and biotechnological utilization of beneficial microorganisms, such as mushrooms, for the benefit of humanity. Recent advancements in mushroom biotechnology will prove successful due to mushrooms’ nature as natural problem solvers, including their ability to enhance nutritional values obtained from agricultural crops, sustained health benefits derived from pharmacologically active substances used to manage human diseases, and improve crop production.
This book will serve as one of the first volumes addressing the usefulness of mushroom biotechnology, giving detailed state-of-the-art information on recent advancements and how the industry could maximize profits. The volume will also assist the pharmaceutical and medical sectors by examining the discovery of novel pharmacological and bioactive compounds that could replace the various adverse effects when using synthetic drugs. It presents a simple, adaptable, reproducible methodology that will help researchers and scientists adopt these methodologies for similar projects.
Readers will find that the book:
Presents recent advances in the application of mushroom biotechnology in various sectors (food, agriculture, and health) for sustainable innovations for optimum benefit of mankind; Details applications of mushrooms for sustainable agriculture through their plant growth-promoting attributes and management of pests and diseases in plants and soils; Discusses the discovery of novel pharmacological substances from mushrooms for applications in the biomedical sector.
Audience
The book is valuable reference work for scientists and researchers working in the fields of pharmaceutical sciences, agricultural microbiology, plant pathology, botany, agriculture, microbiology, biotechnology, nanotechnology, environmental microbiology, and microbial biotechnology.
Edited by:
Charles Oluwaseun Adetunji (Edo State University Uzairue Edo State Nigeria),
Chukwuebuka Egbuna (University of Port-Harcourt,
Rivers State,
Nigeria),
Oluwatosin Ademola Ijabadeniyi (Durban University of Technology,
Durban,
South Africa),
Samantha C. Karunarathna (Chinese Academy of Sciences,
Kunming,
Yunnan,
China)
Imprint: Wiley-Scrivener
Country of Publication: United States
ISBN: 9781394212637
ISBN 10: 1394212631
Pages: 400
Publication Date: 26 May 2025
Audience:
Professional and scholarly
,
Undergraduate
Format: Hardback
Publisher's Status: Forthcoming
Preface xv 1 Application of Mushrooms in the Bioremediation of Environmental Pollutants 1 Isibor Patrick Omoregie, Oluwafemi Adebayo Oyewole, Kayode-Edwards Ihotu, Agbontaen Osagie David, Konjerimam Ishaku Chimbekujwo, Simon Sunday Ameh, Samuel Adeniyi Oyegbade and Charles Oluwaseun Adetunji 1.1 Introduction 2 1.2 Unique Characteristics of Fungi 4 1.3 Specific Contaminants Targeted by Mushrooms 6 1.4 Mechanisms of Mushroom Bioremediation 7 1.5 Absorption and Accumulation of Contaminants by Mushrooms 9 1.6 Transformation and Degradation of Pollutants 10 1.7 Role of Enzymes and Metabolic Processes 12 1.8 Advancements and Research in Mushroom Bioremediation 13 1.9 Emerging Trends in Fungal Bioremediation 15 1.10 Genetic Modification of Mushrooms for Enhanced Bioremediation 16 1.11 Benefits of Mushroom Bioremediation 19 1.12 Challenges and Limitations of Using Mushrooms 21 1.13 Future Prospects and Research Opportunities 22 1.14 Conclusion and Recommendations 24 2 Application of Mushroom in the Management of Pest and Diseases Affecting Agricultural Crops 29 Ruth Ebunoluwa Bodunrinde, Konjerimam Ishaku Chimbekujwo, Oluwafemi Adebayo Oyewole, Charles Oluwaseun Adetunji, Oluwabukola Atinuke Popoola, John Tsado Mathew and Adeyomoye Olorunsola Israel 2.1 Introduction 30 2.2 Properties of Mushroom as Biocontrol Agents (Basidiomycetes) 31 2.3 Mushroom Substrate as Biocontrol Agent for Plant 33 2.4 Mechanism of Action of Mushrooms in the Control of Pests and Diseases 34 2.5 Several Areas Where Mushrooms Can Be Applied 36 2.6 Mushrooms as Disease Control Agents 37 2.7 Conclusion 38 3 Agricultural Applications of Novel Mushroom-Based Nanopesticide 45 Isibor Patrick Omoregie, Oluwafemi Adebayo Oyewole, Adamu Binta Buba, Alhassan Muhammad Alhassan and Charles Oluwaseun Adetunji 3.1 Introduction 46 3.2 Advantages of Nanobiopesticides Over Conventional Pesticides 50 3.3 Mushrooms as Nanobiopesticide Sources 52 3.4 Bioactive Compounds in Mushrooms Suitable for Nanobiopesticide Development 55 3.5 Role of Mushroom Extracts in Nanoparticle Synthesis 56 3.6 Mechanisms of Action of Nanobiopesticides on Pests and Pathogens 57 3.7 Production and Formulation of Nanobiopesticides 60 3.8 Agricultural Applications of Nanobiopesticides 61 3.9 Future Prospects and Research Directions 64 3.10 Recommendation and Conclusion 66 4 Mass Production of Mushroom for Animal Feed 71 Konjerimam Ishaku Chimbekujwo, Ruth Ebunoluwa Bodunrinde, Oluwafemi Adebayo Oyewole, Charles Oluwaseun Adetunji, Oluwabukola Atinuke Popoola, John Tsado Mathew and Adeyomoye Olorunsola Israel 4.1 Introduction 72 4.2 Mushroom 73 4.3 Mushroom Production 74 4.4 Benefits of Feeding Animals with Mushrooms 78 4.5 Conclusion 79 5 Application of Mushrooms in Management of Soil-Borne Parasites, Nematodes, Bacteria and Fungi 85 Aisha Bisola Bello, Abdullahi Idris Dabban, Wuna Muhammad Muhammad, Adioha Amarachi, Joseph Odey Oko, Hammed Opeyemi, Oluwafemi Adebayo Oyewole and Charles Oluwaseun Adetunji 5.1 Introduction 86 5.2 Soil-Borne Parasites, Nematodes, Bacteria, and Fungi 88 5.3 Mushrooms as Biocontrol Agents 98 5.4 Mushroom Species and Biocontrol Potential 102 5.5 Advantages of Mushroom Biocontrol 107 5.6 Challenges and Limitations of Mushroom Bio-Control 108 5.7 Conclusion and Future Outlook 108 6 Production of Stable Enzymes from Mushrooms with Numerous Biomedical Applications 123 Idris Abdullahi Dabban, Olorunshola Lucky Opeyemi, Mustapha Adamu, Bashaku Yakubu Dabban, Auwalu Bala, Oyegbade Samuel Adeniyi, Oluwafemi Adebayo Oyewole and Charles Oluwaseun Adetunji 6.1 Introduction 124 6.2 Classes/Types of Mushrooms 126 6.3 Stable Enzymes Produced by Mushrooms 131 6.4 Biomedical and Biotechnological Applications of Stable Mushroom Enzymes 137 6.5 Some Limitations of Mushroom Enzymes 145 6.6 Conclusion and Future Perspectives 146 7 Relevance of Mushrooms for Biological Control of Diverse Biotic Agent Mitigating Against Agricultural Crops 159 Oluwabukola Atinuke Popoola, Charles Oluwaseun Adetunji, Oluwafemi Adebayo Oyewole, Abel Inobeme and Adeyomoye Olorunsola Israel 7.1 Introduction 160 7.2 Fungal Biopesticides 163 7.3 Mycoparasitism 167 7.4 Nutrient Cycling and Soil Health 170 7.5 Companion Planting 172 7.6 Challenges and Considerations 174 7.7 Conclusion and Future Perspectives 175 8 Discovery and Relevance of Novel Pharmacological Substances from Beneficial Mushrooms 183 Oluwabukola Atinuke Popoola, Charles Oluwaseun Adetunji, Oluwafemi Adebayo Oyewole, Abel Inobeme and Adeyomoye Olorunsola Israel 8.1 Introduction 184 8.2 Bioactive Compounds in Mushrooms 192 8.3 Pharmacological Activities of Mushroom-Derived Compounds 193 8.4 Clinical Applications and Relevance 195 8.5 Challenges and Future Directions 196 9 Application of Mushroom in the Management of Diabetes Mellitus 209 Adeyomoye Olorunsola Israel, Charles Oluwaseun Adetunji, Oluwafemi Adebayo Oyewole, Oluwabukola Atinuke Popoola and John Tsado Mathew 9.1 Introduction 210 9.2 Pathophysiology of Diabetes Mellitus 210 9.3 Mushroom and Its Biomolecules 212 9.4 Mushroom and Health 213 9.5 Therapeutic Potential of Mushroom in the Management of Diabetes Mellitus 214 9.6 Conclusion 216 10 Application of Mushrooms in the Management of Cardiovascular Diseases 221 Enitan Emmanuella Lawal, Frances Iseghohi, Aishat Sani Rabiu, Amarachi Rosemary Osi, Oluwafemi Adebayo Oyewole, Charles Oluwaseun Adetunji, Oluwabukola Atinuke Popoola, and Adeyomoye Olorunsola Israel 10.1 Introduction 222 10.2 Selected Medicinal Mushrooms 224 10.3 Nutritional Composition of Mushrooms 227 10.4 Bioactive Compounds in Mushrooms 229 10.5 Cardioprotective Effect of Mushrooms 232 10.6 Conclusion 233 11 Application of Mushroom in the Regulation of Gut Microbiome and Maintenance of Gut Health 239 Adeyomoye Olorunsola Israel, Charles Oluwaseun Adetunji, Oluwafemi Adebayo Oyewole, Oluwabukola Atinuke Popoola and John Tsado Mathew 11.1 Introduction 240 11.2 Gut Microbiome in Health and Disease 241 11.3 Mushrooms and Their Derived Bioactive Molecules 243 11.4 Health Benefits of Edible Mushroom Associated with Maintenance of Gut Health 245 11.5 Conclusion 246 12 Applications of Mushrooms in the Management of Cancers 251 Tsado Priscilla Yetu, Iseghohi Frances, Sani Rabiu Aishat, Oluwafemi Adebayo Oyewole, Idris Abdullahi Dabban, Charles Oluwaseun Adetunji, Oluwabukola Atinuke Popoola and Adeyomoye Olorunsola Israel 12.1 Introduction 252 12.2 Cancer 253 12.3 Mushrooms 254 12.3.4 Exploring Novel Mushroom-Derived Therapies for Cancer 280 13 Applications of Mushrooms as Immune Boosters 289 Margaret Ikhiwili Oniha, Clement Shina Olusanya, Oluwafemi Adebayo Oyewole, Priscilla Yetu Tsado, Charles Oluwaseun Adetunji, Oluwabukola Atinuke Popoola and Adeyomoye Olorunsola Israel 13.1 Introduction 290 13.2 Mushroom Composites 293 13.3 Β-Glucans and Their Nutritional Components 296 13.4 Antiproliferative and Other Human Health Reactions of Medicinal Mushrooms 297 14 The Influence of Mushroom on the Taphonomic Process of Cadaver 307 Willy Barinem Vidona, Charles Oluwaseun Adetunji and Charity Willy-Vidona 14.1 Introduction 308 14.2 Mushroom and the Fungus Phylogeny 309 14.3 Mushroom Taphonomic Process 310 14.4 Influence of Mushroom on Cadaver Taphonomy 311 14.5 Conclusion 312 15 Role of Nanobiopesticides Derived from Mushrooms: Recent Advances 317 John Tsado Mathew, Charles Oluwaseun Adetunji, Abel Inobeme, Abdulfatai Aideye Otori, Elijah Yanda Shaba, Musah Monday, Yakubu Azeh, Jibrin Noah Akoji, Amos Mamman, Oluwafemi Adebayo Oyewole, Eniola K. I. T. and Mohammed Bello Yerima 15.1 Introduction 318 15.2 Environmental and Health Concerns with Chemical Pesticides 321 15.3 Mushrooms as a Source of Bioactive Compounds 322 15.4 Antimicrobial and Insecticidal Properties of Mushrooms 324 15.5 Nanotechnology and its Applications in Agriculture 325 15.6 Mechanisms of Action of Nanobiopesticides 327 15.7 Benefits and Advantages of Nanobiopesticides 328 15.8 Conclusion and Future Perspectives 329 16 Nutraceutical, Mineral, Proximate Constituents from Beneficial Mushrooms 337 John Tsado Mathew, Abel Inobeme, Charles Oluwaseun Adetunji, Abdulfatai Aideye Otori, Elijah Yanda Shaba, Musah Monday, Yakubu Azeh, Ismail Haruna, Amos Mamman, Jemkur Maurice, Oluwafemi Adebayo Oyewole, Eniola K. I. T. and Mohammed Bello Yerima 16.1 Introduction 338 16.2 Nutraceutical Constituents of Mushrooms 339 16.3 Mineral Constituents of Mushrooms 342 16.4 Proximate Constituents of Mushrooms 345 16.5 Variation among Mushroom Species 347 16.6 Health Implications and Potential Benefits 348 16.7 Conclusion 352 17 Application of Mushrooms in the Promotion of Longevity 359 Victory Igiku, Charles Oluwaseun Adetunji, Oluwafemi Adebayo Oyewole, Eniola K. I. T. and Mohammed Bello Yerima 17.1 Introduction 359 17.2 Health Benefits of Mushrooms 361 17.3 Conclusion 365 References 366 Index 371
Charles Oluwaseun Adetunji, PhD, is a professor in the Department of Microbiology at the Edo University Iyamho, in Edo State, Nigeria. Currently, he is the Director of Intellectual Properties and Technology Transfer and Chairman of the Committee on Research Grants at EUI. He has won several scientific awards and grants from renowned academic bodies such as the Council of Scientific and Industrial Research (CSIR) India. He has published more than 600 papers in peer-reviewed national and international journals as well as more than 50 books, 340 book chapters, and many scientific patents. Chukwuebuka Egbuna, PhD, is a chartered chemist and academic researcher. He has published numerous articles in international journals of repute and edited over 20 internationally published books. He serves as a reviewer and editorial board member of several journals and a member of the Institute of Chartered Chemists of Nigeria, the Nigerian Society of Biochemistry and Molecular Biology, and the Royal Society of Chemistry. His primary research interests include biochemistry, phytochemistry, pharmacology, nutrition and toxicology, food and medicinal chemistry, and analytical biochemistry. Oluwatosin Ademola Ijabadeniyi, PhD, is a professor in the Department of Biotechnology and Food Science, Durban University of Technology, South Africa. He has published numerous scientific papers, edited one book, and authored four books. His work in this field has also earned him several awards including an Association of Commonwealth Universities fellowship and an Association of Public Health Libraries Centers for Disease Control fellowship. Samantha C. Karunarathna, PhD, is a professor at Qujing Normal University, China. He has published over 360 publications and co-authored two books. His current research interests are taxonomy, phylogeny, and domestication of wild edible and medicinal mushrooms.
