Muscular and Skeletal Anomalies in Human Trisomy in an Evo-Devo Context: Description of a T18 Cyclopic...

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Rui Diogo Christopher M. Smith

Muscular and Skeletal Anomalies in Human Trisomy in an Evo-Devo Context

Description of a T18 Cyclopic Fetus and Comparison Between Edwards (T18), Patau (T13) and Down...

Rui Diogo, Christopher M. Smith, Janine M. Ziermann , Julia Molnar

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English

CRC Press
29 October 2019

Anatomy; Medical genetics; Paediatric medicine; Surgery

This book focuses on human anatomy and medicine and specifically on both muscular and skeletal birth defects in humans with trisomy. Moreover, this book also deals with Down syndrome, which is one of the most studied human syndromes and, due to its high incidence and the fact that individuals with this syndrome often live until adulthood, is of special interest to the scientific and medical community.

This new line of inquiry is addressed to a wide audience, including medical researchers, physicians, surgeons, medical and dental students, pathologists, and pediatricians, among others, while also being of interest to developmental and evolutionary biologists, anatomists, functional morphologists, and zoologists.

By: Rui Diogo, Christopher M. Smith, Janine M. Ziermann, Julia Molnar, Marjorie C. Gondre-Lewis
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 254mm, Width: 178mm,
Weight: 453g
ISBN: 9780367377793
ISBN 10: 0367377799
Pages: 224
Publication Date: 29 October 2019
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Topics and purpose of this book. The musculoskeletal system of a 28-week human Trisomy 18 cyclopia fetus. Comparative anatomy of muscular anomalies of Trisomies 13, 18, and 21. Cyclopia, trisomic anomalies, and order versus chaos in development and evolution. Digits and muscles: topology-directed muscle attachment. Evolutionary theory and mouse models for Down syndrome. Appendix A - Dissection photographs of Trisomy 18 human cyclopia fetus. Appendix B - 3-D renders of Trisomy 18 human cyclopia fetus CT scan data. References. Index.

Diogo, Rui; Smith, Christopher M.; Ziermann, Janine M.; Molnar, Julia; Gondre-Lewis, Marjorie C.; Sandone, Corinne; Bersu, Edward T.; Aziz, Mohammed Ashraf