This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography.
By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.
Edited by:
Michael Baumann, Mechthild Krause, Nils Cordes Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Country of Publication: Germany Edition: 2016 ed. Volume: 198 Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 13mm
Weight: 4.439kg ISBN:9783662496497 ISBN 10: 3662496496 Series:Recent Results in Cancer Research Pages: 201 Publication Date:23 June 2016 Audience:
Professional and scholarly
,
Undergraduate
Format:Hardback Publisher's Status: Active
Michael Baumann, University of Technology, Dresden, Germany.Mechthild Krause, University of Technology, Dresden, Germany.Nils Cordes, University of Technology, Dresden, Germany.