Molecular Immunology

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B. D. Hames (Department of Biochemistry and Molecular Biology, Department of Biochemistry and Molecular Biology, University of Leeds) D. M. Glover (Department of Anatomy and Physiology, Department of Anatomy and Physiology, University of Dundee)

Molecular Immunology

B. D. Hames (Department of Biochemistry and Molecular Biology, Department of Biochemistry and Molecular Biology, University of Leeds), D. M. Glover (Department of Anatomy and Physiology, Department of Anatomy and Physiology, University of Dundee)

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English

Oxford University Press
08 February 1996

Immunology; Biochemical immunology; Molecular biology

Series: Frontiers in Molecular Biology

The book is a collection of up-to-date reviews by major researchers in the field of the fast-moving area of modern immunology.

Its wide scope, depth of coverage, well-illustrated text, and the eminence of the authorship make it unique in its field.

Over 1900 literature reference are cited.

So much has happened in immunology since publication of the first edition of this popular book seven years ago that the second edition is a major new work.

The chapters on mechanism and control of immunoglobulin genes by Fred Alt and his colleagues, T-cell antigen receptor genes by Mark Davis and Yeuh-hsui Chien, T lymphocyte signal transduction by Cox Terhorst et al, and the complement system by Ken Reid are all major updates and extensions of their first edition contributions.

In addition, the second edition contains new chapters by David Jewell and Ian Wilson on the structure and function on MHC class I and class II antigens, by John Monaco on molecular mechanisms of antigen processing.

By Gerry Klaus on B cell activation, and by Martine Verhoeyen and John Windust in recent advances by antibody engineering.

Edited by: B. D. Hames (Department of Biochemistry and Molecular Biology Department of Biochemistry and Molecular Biology University of Leeds), D. M. Glover (Department of Anatomy and Physiology, Department of Anatomy and Physiology, University of Dundee)
Imprint: Oxford University Press
Country of Publication: United Kingdom
Edition: 2nd Revised edition
Volume: 11
Dimensions: Height: 246mm, Width: 189mm, Spine: 22mm
Weight: 1g
ISBN: 9780199633784
ISBN 10: 0199633789
Series: Frontiers in Molecular Biology
Pages: 404
Publication Date: 08 February 1996
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

1: Rusty Lansford, Ami Okada, Jianzhu Chen, Eugene M. Oltz, T. Keith Blackwell, Frederick W. Alt, and Gary Rathbun: Mechanism and control of immunoglobulin gene rearrangement 2: Mark M. Davis and Yueh-hsui Chien: T cell antigen recepotor genes 3: Cox Terhorst, Mark Exley, Frank Staal and Hergen Spits: T lymphocyte signal transduction 4: David Jewell and Ian A. Wilson: Structure and function of MHC class I and class II antigens 5: John J. Monaco: Molecular mechanisms of antigen processing 6: Gerry G.B. Klaus: B cell activation 7: Martine E. Verhoeyen and John H.C. Windust: Advances in antibody engineering 8: Kenneth B.M. Reid: The complement system

Reviews for Molecular Immunology

Its chapters are written by leading experts, and the information is presented in a comprehensive yet direct manner. The most striking feature of the book is the number of references cited. Close to 2,000 publications, all with complete titles and authors, are referred to. . . . On the whole, presentations are even and well thought out. --Quarterly Review of Biology An excellent second edition on important topics in molecular immunology. It covers in detail the generation and application of engineered antibodies and the molecular mechanisms of antigen presentation; immunoglobulin and T cell receptor rearrangements and expression; and the activation of B cells, T cells, and the complement cascade. The book incorporates contributions from recognized experts, most of whom work for academic research institutions in the U.S....Excellent and comprehensive. --Doody's Health Sciences Book ReviewListed in Books of Interest in Journal of Medicinal Chemistry