Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health provides a comprehensive overview of mitochondrial physiology throughout the human life span, as well as the effect of molecules of vegetal origin on mitochondrial health. The editor has lined up a team of worldwide experts to cover the most exciting and high-impact advancements of research in this area.
This book is structured into two parts that provide a balance of both foundational and applied content. Part I provides an overview of mitochondrial physiology including its structure, dynamics, biogenesis, membranes, DNA transcription, and translation in the mitochondria. Part I also covers other themes such as apoptosis. Part II then covers the effect of specific vegetable-derived molecules on mitochondrial health, including anthocyanins, caffeine, cannabinoids, carnosic and rosmarinic acids, citrus flavonoids, polyphenols, pterostilbene, resveratrol, and sulforaphane, among others.
Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health is a complete resource for researchers in this exciting field. Its comprehensive coverage makes it particularly interesting to bioscience researchers willing to understand the foundations of mitochondrial physiology throughout the human life span. Clinician researchers, MDs, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the health effects of vegetal origin molecules on the organelle.
Part I - Overview of Mitochondrial Physiology 1. Mitochondria: Ultrastructure, Dynamics, Biogenesis and Main Functions 2. Mitochondrial biogenesis and mitophagy 3. DNA transcription and translation in the mitochondria 4. Mitochondrial redox biology: reactive species production and antioxidant defenses 5. Mitochondria and apoptosis 6. Mitochondria-Associated Membranes in the Maintenance of Cell Homeostasis Part II - The effects of plant molecules on the mitochondria in health and disease 7. Biopharmaceutical Properties of Natural Products 8. Carnosic acid and brain mitochondria 9. Rosmarinic acid and the mitochondria 10. The effects of sulforaphane on the mitochondria 11. Cannabinoids and mitochondria 12. Anthocyanins, effects in mitochondria and metabolism 13. Preclinical evidence of the therapeutic role of pterostilbene: focus on the mitochondria 14. Polyphenols attenuate mitochondrial dysfunction induced by amyloid peptides 15. Plant molecules to treat eye mitochondria 16. Mitochondria as a target for monoterpenes 17. Baccharis trimera phytochemicals and the mitochondria 18. Citrus flavonoids and the mitochondria 19. Caffeine and the brain mitochondria 20. Curcumin and the mitochondria 21. Catechins, neuroprotection and brain mitochondria 22. The effects of catechins on the cardiac mitochondria 23. Possible Roles of Garlic and Its Bioactive Components on Mitochondrial Function in Physiological and Pathological Conditions 24. Resveratrol effects on skeletal muscle mitochondria and contractile function 25. Antiaging effects of natural agents in the skin: focus on the mitochondria 26. Role of quercetin in the glial mitochondria: Implications for health and disease 27. The Therapeutic Effects of Lycopene on Mitochondrial Function in Human Diseases 28. Ascorbic acid and the mitochondria 29. Soy isoflavones, mitochondria, and cell fate 30. Resveratrol and the brain mitochondria 31. The role of plant molecules on the prevention and treatment of mitochondriarelated intoxication 32. Mitochondrial toxicity induced by plant molecules 33. Mitohormesis
Marcos Roberto de Oliveira earned his bachelor's degree in Biological Sciences at Federal University of Rio Grande do Sul (UFRGS) in 2005, followed by a Master's and a Ph.D. in Biochemistry from the same institution. Dr. Marcos Roberto de Oliveira's research during this period focused on the toxic effects of vitamin A on mitochondria. Currently, Dr. Marcos Roberto de Oliveira is a professor at UFRGS. His current research focuses on the mechanism of action by which natural molecules promote mitochondrial protection in human and animal cells.
