Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial...

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Venkatesan Jayaprakash (Birla Institute of Technology, Dept. of Pharmaceutical Sciences and Technology, India) Daniele Castagnolo (King's College London, UK)

Medicinal Chemistry of Neglected and Tropical Diseases

Advances in the Design and Synthesis of Antimicrobial Agents

Venkatesan Jayaprakash (Birla Institute of Technology, Dept. of Pharmaceutical Sciences and Technology, India), Daniele Castagnolo (King's College London, UK), Yusuf Özkay

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English

CRC Press
31 March 2021

Pharmacology; Tropical medicine; Botany & plant sciences; Pharmaceutical technology

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.

Edited by: Venkatesan Jayaprakash (Birla Institute of Technology Dept. of Pharmaceutical Sciences and Technology India), Daniele Castagnolo (King's College London, UK), Yusuf Özkay
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 254mm, Width: 178mm,
Weight: 453g
ISBN: 9780367779252
ISBN 10: 0367779250
Pages: 380
Publication Date: 31 March 2021
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Dr. Venkatesan Jayaprakash graduated (B. Pharmacy) from Madras Medical College, Madras in Pharmaceutical Sciences. He did his post graduation (M. Pharmacy) in Pharmaceutical Chemistry from Banaras Hindu University, Varanasi. He received his Ph.D. from Birla Institute of Technology, Mesra. Since 2004, he is working as a faculty member in Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra. He is medicinal chemist working in the area of drug design and development against therapeutically validated targets. His current research interest is on developing new chemical entities for the treatment of Tuberculosis (Mycobactin synthetase inhibitors), Viral infections (protease and methyltransferase inhibitors), Cancer (CYP-1A & 1B and Cdk-4 inhibitors) and Depression (MAO inhibitors). Dr. Daniele Castagnolo is Lecturer of Pharmaceutical Chemistry at the Institute of Pharmaceutical Science at King’s College London. Dr. Castagnolo’s research interests range widely from organic synthetic chemistry to medicinal chemistry and are mainly focused on the design and discovery of bioactive molecules active against Mycobacterium tuberculosis, drug-resistant Gram+/- bacteria and viruses. In addition, Dr. Castagnolo’s research group is interested in the development of novel biocatalytic and chemoenzymatic methods for the manufacturing of druglike compounds. Prof. Yusuf Özkay works in the Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskişehir-Turkey. Synthesis and biological evaluation of new enzyme inhibitors, central nervous system related compounds, anticancer, and antimicrobial agents constitute his main research areas. He has more than 50 articles in the journals covered by Science Citation Index, over 100 presentations in the international congresses, and more than 500 citations made to the works of him.