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Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine.
This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs.
Volume editor:
Trygve Tollefsbol
Imprint: Academic Press Inc
Country of Publication: United States
Edition: 2nd edition
Dimensions:
Height: 276mm,
Width: 216mm,
Weight: 2.510kg
ISBN: 9780128239285
ISBN 10: 012823928X
Series: Translational Epigenetics
Pages: 970
Publication Date: 26 August 2021
Audience:
Professional and scholarly
,
Undergraduate
Format: Paperback
Publisher's Status: Active
Section A Overview 1. Advances in medical epigenetics Section B General medical aspects of epigenetics 2. Environmental epigenetic epidemiology 3. Lifestyle and preventive medical epigenetics 4. Environmental medical epigenetics: A review of epigenetically induced medical risks generated from exposures in our air, food, and personal products 5. Behavioral medical epigenetics 6. Medical epigenetics and twins 7. Epigenetic biomarkers of disease 8. Prognostic epigenetics Section C Epigenetics of system disorders 9. Autoimmune disease and epigenetics 10. Epigenetics of pulmonary diseases 11. Cardiovascular disorders and epigenetics 12. Epigenomics of intestinal disease 13. Epigenetics of skin disorders 14. Epigenetics in bone and joint disorders 15. Epigenetics of muscle disorders 16. Reproductive disease epigenetics 17. Epigenetics in ocular medicine Section D Multi-system medical epigenetics 18. Pediatric diseases and epigenetics 19. Epigenetics of infectious diseases 20. Clinical utility of solid tumor epigenetics 21. Epigenetics in acute myeloid leukemia 22. Epigenetic regulation in cancer metastasis 23. Epigenetics in exercise science and sports medicine Section E Bioinformatics of epigenetic medicine 24. Machine learning in epigenetic diseases Section F Pharmacology of epigenetics 25. Epigenetics in toxicology and drug development 26. Pharmacoepigenomics in neurodegenerative diseases Section G Therapeutic epigenetics 27. Therapeutics and DNA methylation inhibitors 28. Histone deacetylase inhibitors in medical therapeutics 29. Sirtuins as NAD+-dependent deacetylases and their potential in medical therapy 30. Experimental approaches toward histone acetyltransferase modulators as therapeutics 31. Histone methylation modifiers in medical therapeutics 32. Modulation of noncoding RNAs (ncRNAs) and their potential role as therapeutics 33. Nutrients and phytonutrients as promising epigenetic nutraceuticals 34. Epigenetics of pain management 35. Precision medical epigenetics 36. Epigenetics and regenerative medicine 37. Stem cell epigenetics in medical therapy 38. The clinical landscape of HDAC inhibitors Section H Medical epigenetics: Future prospects 39. Epigenetics: Future prospective in human disorders and therapeutics 40. Prospective advances in medical epigenetics
Dr. Tollefsbol is a Distinguished Professor of Biology and a Senior Scientist in the O’Neal Comprehensive Cancer Center, Integrative Center for Aging Research, Nutrition Obesity Research Center, University Wide Microbiome Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol trained as a Postdoctoral Fellow and Assistant Research Professor with members of the National Academy of Science at Duke University and the University of North Carolina. He earned doctorates in molecular biology and osteopathic medicine from the University of North Texas Health Sciences Center and his bachelor’s degree in Biology from the University of Houston. He has received prior funding from the NCI, NHLBI, NIMH and other federal institutes as well as the Glenn Foundation for Medical Research, Susan G. Komen for the Cure, the American Federation for Aging Research (AFAR), and the American Institute for Cancer Research (AICR) among many other sources.
Reviews for Medical Epigenetics
This volume is wonderfully comprehensive and addresses all the relevant aspects of medical epigenetics. It will take a true expert in the field to digest all the information available in the collected chapters of this publication. Most commonly, readers will focus on one or a few chapters of most relevance to their own practice or research. Overall, however, this is an outstanding resource book that brings together all the most up-to-date discussions of medical epigenetics in one place. This is a must-have book for any medical school library. -- (c) Doody's Review Service, 2021, Mark F. Sanders, PhD, reviewer, expert opinion