Lysosomal Disorders of the Brain: Recent Advances in Molecular and Cellular Pathogenesis and Treatment...

— —

Frances Platt (, Glycobiology Institute, Department of Biochemistry, University of Oxford, UK) Steven Walkley (, Department of Neuroscience, Albert Einstein College of Medicine, New York, USA)

Lysosomal Disorders of the Brain

Recent Advances in Molecular and Cellular Pathogenesis and Treatment

Frances Platt (, Glycobiology Institute, Department of Biochemistry, University of Oxford, UK), Steven Walkley (, Department of Neuroscience, Albert Einstein College of Medicine, New York, USA)

$560

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

Oxford University Press
01 December 2003

Metabolism; Hereditary diseases & disorders; Neurology & clinical neurophysiology; Pathology; Neurosciences

Lysosomal storage diseases are inherited metabolic disorders characterized by severe pathology, typically involving the brain.

Although individually rare, they collectively represent a significant group of diseases that primarily present in early infancy or childhood.

In recent years considerable progress has been made in understanding the molecular mechanisms that lead to disordered function of the lysosomal system and to lysosomal storage.

Unravelling the basis for these diseases is providing unique insight into the normal biology of cells and pointing the way to the development of therapeutic strategies for their treatment.

Lysosomal Disorders of Brain details recent advances in the molecular and cellular pathologies of these diseases and in the development of effective therapies. After an overview of the biology of the endosomal-lysosomal system and the types of diseases resulting from defects in this system, the book describes in detail the molecular mechanisms of storage, model systems and pathophysiological mechanisms, and finally, new advances toward treatment.

With each chapter written by leading experts in their field, this book will be valuable for scientists and clinicians in helping them understand the role of lysosomes in normal cells and mechanisms underlying these disorders, how they can be diagnosed, and the treatment options that are currently available.

Edited by: Frances Platt ( Glycobiology Institute Department of Biochemistry University of Oxford UK), Steven Walkley (, Department of Neuroscience, Albert Einstein College of Medicine, New York, USA)
Imprint: Oxford University Press
Country of Publication: United Kingdom
Dimensions: Height: 248mm, Width: 173mm, Spine: 31mm
Weight: 1g
ISBN: 9780198508786
ISBN 10: 0198508786
Pages: 478
Publication Date: 01 December 2003
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Reviews for Lysosomal Disorders of the Brain: Recent Advances in Molecular and Cellular Pathogenesis and Treatment

. . . this book is highly recommended . . for those readers wanting to get a clear and straightforward overview of LSDs . . . then this well-written book is a worthwhile investment. * Nature Cell Biology, Vol 6, Number 11 *