Ligand-Binding Basics: Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity...

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Jannette Carey (Princeton University)

Ligand-Binding Basics

Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity

Jannette Carey (Princeton University)

$197.95

Hardback

Forthcoming
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English

John Wiley & Sons Inc
02 October 2025

Chemistry

A concise and accessible textbook covering ligand-binding theory in chemistry, biology, and drug development

In Ligand-binding Basics: Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity, accomplished chemist Professor Jannette Carey introduces ligand binding in a thorough and practical way for those new to the topic, as well as anyone seeking a connection between theory and experiment. Using a minimum of mathematical formalism, this book offers analytical rigor while remaining accessible to non-specialist practitioners. It provides readers with the skills they need to analyze their own binding data or published results, helping them develop an intuitive grasp of ligand-binding phenomena integrated with structural and thermodynamic understanding.

Topics covered include:

Application of the principles of equilibrium, mass action, and mass balance to derive the basic equations that describe all binding processes Recommended approaches for plotting and graphical analysis of binding data Strategies for designing, analyzing, interpreting, and troubleshooting experiments from the perspective of ligand-binding theory Review of selected examples that illustrate integration of structural and thermodynamic analysis

Perfect for students and educators in chemistry, biochemistry, molecular biology, and pharmaceutical science, Ligand-binding Basics will also appeal to practitioners who aim to study ligand binding in any molecular system.

By: Jannette Carey (Princeton University)
Imprint: John Wiley & Sons Inc
Country of Publication: United States [Currently unable to ship to USA: see Shipping Info]
Dimensions: Height: 244mm, Width: 170mm,
ISBN: 9781119878421
ISBN 10: 111987842X
Pages: 256
Publication Date: 02 October 2025
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Forthcoming

Jannette Carey has been a member of the Chemistry faculty at Princeton University for over thirty years, where she developed and teaches a two-term sequence in biophysical chemistry that is accessible to early graduate and advanced undergraduate students in a wide range of disciplines. Her biophysical research is focused on unifying the thermodynamic and structural basis for macromolecular interactions.