PRIZES to win! PROMOTIONS

Close Notification

Your cart does not contain any items

Left-Right Asymmetry in Vertebrate Development

M.L. López-Gracia M.A. Ros

$370.95   $296.98

Paperback

Not in-store but you can order this
How long will it take?

QTY:

English
Springer-Verlag Berlin and Heidelberg GmbH & Co. K
11 December 2006
Externally the vertebrate body plan presents a bilateral symmetry in relation to the midline. However, inside the body the distribution of the visceral organs follows a very particular pattern that is not symmetrical in relation to the midline. The last 10 years have seen remarkable advances in our understanding of how the internal asymmetries typical of the vertebrate body are established and controlled. The use of different development models has permitted to uncover fascinating ways of creating asymmetry, like the activity of the nodal cilia. A host of studies has also unravelled the involvement of many genes in the left right patterning pathway. Based on this knowledge the genetic basis of human laterality defects are beginning to be revealed. It is a major challenge now to understand how all these genes control left right development as well as the complex set of interactions established between them.
By:   ,
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Publication:   Germany
Edition:   2007 ed.
Volume:   188
Dimensions:   Height: 235mm,  Width: 155mm,  Spine: 8mm
Weight:   415g
ISBN:   9783540363477
ISBN 10:   3540363475
Series:   Advances in Anatomy, Embryology and Cell Biology
Pages:   126
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
Establishment of Left-Right Asymmetry.- Signaling Pathways with a Predominant Role in Left-Right Patterning.- Mouse Models of Laterality.- Genetics of Human Alterations of Organ Situs.- Concluding Remarks.

See Also