In this issue of Otolaryngologic Clinics, guest editors Drs. Inna A. Husain and Nikki Johnston bring their considerable expertise to the topic of Laryngopharyngeal Reflux. Although it is suggested that laryngopharyngeal reflux disease (LPRD) accounts for up to 30% of outpatient otolaryngology visits, lack of formal diagnostic criteria, ease of testing, and varied treatment practices can lead to delay in care and high social/economic burden. In this edition, top experts review up-to-date information on pathophysiology of LPRD, including typical and atypical manifestations, role of diagnostic testing, updated treatment guidelines, and future directions of LPRD management.
Contains 14 relevant, practice-oriented topics including pediatric laryngopharyngeal reflux; microbiota, gut health, and LPRD; chronic cough and pulmonary manifestations of LPRD; the role of surgical intervention in LPRD; future directions for LPRD; and more Provides in-depth clinical reviews on laryngopharyngeal reflux, offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
Introduction to Laryngopharyngeal Reflux Disease Pathophysiology of Laryngopharyngeal Reflux Disease: The Reflux vs Reflex Theory Pepsin, Mucosal Injury, and Pathophysiology of Non-acid Reflux Microbiota, Gut Health, and Laryngopharyngeal Reflux Disease Diagnostic Testing for Laryngopharyngeal Reflux Disease: The Role of 24-hour Hypopharyngeal-Esophageal Multichannel Intraluminal Impedance-pH Monitoring Neural-Mediated Laryngopharyngeal Reflux Disease and the Role of Esophageal Dysmotility What’s with the Lump in the Throat? Globus, Dysphagia, and the Role of the Upper Esophageal Sphincter in Laryngopharyngeal Reflux Disease Dysphonia and Laryngopharyngeal Reflux Chronic Cough and Pulmonary Manifestations of Laryngopharyngeal Reflux Disease Extralaryngeal Manifestations of Laryngopharyngeal Reflux Disease Pediatric Laryngopharyngeal Reflux: Epidemiology, Clinical Presentation, Diagnosis, and Therapeutic Outcomes Decision Making in the Managment of Laryngopharyngeal Reflux Disease: Antacids, Alginates, and the Role of Diet The Role of Surgical Intervention in Laryngopharyngeal Reflux Disease Future Directions in Managing and Treating Laryngopharyngeal Reflux Disease for Improving Patient Care