This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. It describes areas of progress in the laboratory and clinic and discusses aspects of cellular organelles. It also covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. The recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.
Edited by:
Sang Geon Kim Imprint: CRC Press Inc Country of Publication: United States Dimensions:
Height: 234mm,
Width: 156mm,
Spine: 18mm
Weight: 476g ISBN:9781466588110 ISBN 10: 146658811X Pages: 234 Publication Date:11 September 2013 Audience:
College/higher education
,
General/trade
,
Primary
,
ELT Advanced
Format:Hardback Publisher's Status: Active
Cellular Organelle-based Renal Toxicity. Transcriptomic Approaches. Proteomic Approaches. Metabolomic Approaches. Molecular Modeling – Molecular Design. Systems Biological Approaches. Virtual Cell. Clinical Implication of Renal Toxicology. Molecular Pathology of Renal Fibrosis. Classification of Nephrotoxicants.