Over the last decade the development of new molecular biology tools, advanced microscopy, live imaging and systems biology approaches have revolutionized our conception of how embryonic development proceeds. One fundamental aspect of development biology is the concept of morphogenesis: understanding how a group of multipotent cells organize and differentiate into a complex organ. In Kidney Development: Methods and Protocols, expert researchers in the field detail different approaches to tackle kidney development. These approaches include culture and live imaging aspects of kidney development, analyzing the 3-dimensional aspects of branching morphogenesis as well as nephrogenesis, manipulation of the gene/protein expression during kidney development as well as in the adult kidney, and how to assess kidney malformation and disease. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Kidney Development: Methods and Protocols seeks to aid scientists in the further study of the process of morphogenesis which is fundamental important not only for studying developmental biology but also for regenerative medicine.
Edited by:
Odyssé Michos Imprint: Humana Press Inc. Country of Publication: United States Edition: 2012 ed. Volume: 886 Dimensions:
Height: 254mm,
Width: 178mm,
Spine: 30mm
Weight: 1.005kg ISBN:9781617798504 ISBN 10: 1617798509 Series:Methods in Molecular Biology Pages: 415 Publication Date:27 May 2012 Audience:
College/higher education
,
Further / Higher Education
Format:Hardback Publisher's Status: Active