Introduction to Biomaterials: Basic Theory with Engineering Applications

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C. Mauli Agrawal (University of Missouri, Kansas City) Joo L. Ong (University of Texas, San Antonio)

Introduction to Biomaterials

Basic Theory with Engineering Applications

C. Mauli Agrawal (University of Missouri, Kansas City), Joo L. Ong (University of Texas, San Antonio), Mark R. Appleford (University of Texas, San Antonio) , Gopinath Mani (Abbott)

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English

Cambridge University Press
20 November 2025

Biomedical engineering; Biochemical engineering; Biotechnology; Mechanical engineering

Series: Cambridge Texts in Biomedical Engineering

Revised and updated throughout, the second edition of this succinct textbook provides the perfect introduction to biomaterials, linking the fundamental properties of metals, polymers, ceramics and natural biomaterials to the unique advantages and limitations surrounding their biomedical applications. New chapters on protein chemistry and interactions, immunology and tissue response, and biocompatibility round out student understanding. Clinical concerns such as sterilization, surface modification, cell-biomaterial interactions, drug delivery systems and tissue engineering are discussed, giving students insight into real-world challenges associated with biomaterials engineering. Key concepts are summarized alongside the text, allowing students to identify the most vital information. The final chapter discusses clinical applications, challenging students to consider future industrial possibilities. Concise enough to be taught in one semester, requiring only a basic understanding of biology, accompanied by over 180 end-of-chapter problems, and featuring color figures throughout, this accessible textbook continues to be ideal for students of engineering, materials science and medicine.

By: C. Mauli Agrawal (University of Missouri Kansas City), Joo L. Ong (University of Texas, San Antonio), Mark R. Appleford (University of Texas, San Antonio), Gopinath Mani (Abbott)
Imprint: Cambridge University Press
Country of Publication: United Kingdom
Edition: 2nd Revised edition
Weight: 1.223kg
ISBN: 9781108841399
ISBN 10: 1108841392
Series: Cambridge Texts in Biomedical Engineering
Pages: 522
Publication Date: 20 November 2025
Audience: College/higher education , A / AS level
Format: Hardback
Publisher's Status: Active

Preface; 1. Introduction; 2. Basic properties of materials; 3. Metals: structure and properties; 4. Polymers; 5. Ceramics; 6. Natural biomaterials; 7. Surface modification; 8. Characterization of biomaterials; 9. Biological systems; 10. Protein chemistry and interactions; 11. Cell-biomaterial interactions; 12. Host responses to biomaterials; 13. Biocompatibility testing; 14. Tissue engineering; 15. Drug delivery systems; 16. Sterilization of biomedical implants; 17. Clinical applications; Index.

C. M. Agrawal is the Chancellor of the University of Missouri-Kansas City. His research specializes in the area of orthopedic and cardiovascular biomaterials/implants. During his professional career, he has authored more than 300 scientific publications, 18 patents and has served on the editorial boards of various scientific journals. He is a Fellow of the National Academy of Inventors, a Fellow of the Biomaterials Science and Engineering, a Fellow of the American Institute for Medical and Biological Engineering. Joo L. Ong is the Senior Associate Dean of Administration and Graduate Studies and the USAA Foundation Distinguished Professor of Biomedical Engineering in the Klesse College of Engineering and Integrated Design at the University of Texas at San Antonio. His research focuses on modification and characterization of biomaterials surfaces for dental and orthopaedic applications, tissue engineering ceramic scaffolds, protein-biomaterial interactions, and bone-biomaterial interactions. He is an Associate Editor for the Journal of Biomedical Materials Research – Part B, a Fellow of the National Academy of Inventors, a Fellow of the American Institute for Medical and Biological Engineering, a Fellow of the Biomaterials Science and Engineering, and a Fellow of the Biomedical Engineering Society. Mark R. Appleford is the Associate Vice Provost – Undergraduate Studies at the University of Texas at San Antonio and an Associate Professor of Biomedical Engineering in the Klesse College of Engineering and Integrated Design at the University of Texas at San Antonio. His research focuses on tissue-biomaterial interactions, cellular engineering, reconstructive tissue engineering, and biocompatibility. Gopinath Mani is the Principal Scientist at Abbott, focusing on surface modification and characterization of biomaterials, nanomaterials and nanomedicine, biodegradable metals and drug delivery systems. He is the Program Chair for the Surface Characterization and Modification Special Interest Group of the Society for Biomaterials, a co-Chair for the 2019 Society for Biomaterials Annual Meeting, and has developed and taught numerous graduate-level programs in biomaterials engineering.

Reviews for Introduction to Biomaterials: Basic Theory with Engineering Applications

'Introduction to Biomaterials is an excellent starting point for students new to the field. It clearly explains foundational concepts and effectively connects theory with real-world biomedical engineering applications. This book is a valuable resource for understanding the role of biomaterials in modern medical and technological advancements.' Gianluca D'Ippolito, University of Miami 'I am excited to endorse Introduction to Biomaterials by Professor Agrawal and his colleagues. As a teacher of Materials Science courses and with research interest in biomaterials, I feel that the book will be helpful to a diverse group of people from undergraduate students to practicing engineers in the industry.' Sarit Bhaduri, University of Toledo 'This comprehensive textbook offers a clear introduction to both fundamental and advanced topics in biomaterials. Ideal for classroom use, it includes well-designed homework problems and covers classical as well as emerging concepts. Its balanced depth and clarity make it an excellent choice for introductory courses in this rapidly evolving field.' Kyriacos A. Athanasiou, University of California 'This outstanding textbook masterfully connects fundamental material structure – properties relationships to real-world implant applications. It also provides excellent coverage of natural materials, nanomaterials, tissue engineering, drug delivery, surface science topics, materials characterization, and biocompatibility testing, all enriched by numerous figures and tables. With clear learning goals and many examples in each chapter, students will be able to learn and apply concepts and use the text as a resource in their professional careers.' Joel D. Bumgardner, University of Memphis