Insomnia Disorder: Epidemiology, Causes, and Pharmacotherapy

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Jaime M. Monti (Professor, Department of Pharmacology and Therapeutics, School of Medicine, Clinics Hospital, University of the Republic, Uruguay) S.R. Pandi-Perumal (President and Chief Executive Officer, Somnogen Canada Inc, Canada)

Insomnia Disorder

Epidemiology, Causes, and Pharmacotherapy

Jaime M. Monti (Professor, Department of Pharmacology and Therapeutics, School of Medicine, Clinics Hospital, University of the Republic, Uruguay), S.R. Pandi-Perumal (President and Chief Executive Officer, Somnogen Canada Inc, Canada)

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English

Academic Press Inc
01 November 2023

Neurology & clinical neurophysiology; Pharmacology; Neurosciences

The field of sleep pharmacology is dynamic in nature and rapid advances are occurring in the field. For example, screening for new drug candidates, development of new drugs, identification of molecular targets, and works related to its efficacy and safety profiles. Furthermore, this leads to the development of evidence-based therapeutic guidelines. Insomnia Disorder: Epidemiology, Causes, and Pharmacotherapy consolidates the latest developments into one volume. It provides the latest, up-to-date knowledge regarding sleep and sleep therapeutics for sleep physicians, sleep researchers, psychiatrists, and any medical professional interested in the interdisciplinary areas of sleep therapeutics. Chapters include topics such as neurobiology, neurotransmitters, regulation of sleep and wakefulness, and overview of all current pharmacotherapies for insomnia.

Edited by: Jaime M. Monti (Professor Department of Pharmacology and Therapeutics School of Medicine Clinics Hospital University of the Republic Uruguay), S.R. Pandi-Perumal (President and Chief Executive Officer, Somnogen Canada Inc, Canada)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 229mm, Width: 152mm,
ISBN: 9780128234129
ISBN 10: 0128234121
Pages: 300
Publication Date: 01 November 2023
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

1. Neurobiology of sleep and waking 2. Neurotransmitters and sleep 3. Regulation of sleep and wakefulness (two-process model of sleep and three-process model of alertness) 3. Chronobiotics and chronohypnotics 4. Normal sleep in children adolescents, adults, and older adults 5. Insomnia: Overview and classification 6. Insomnia characteristics in children, adolescents, adults, and older adults 7. Mechanism of action of presently available hypnotic drugs 8. Pharmacokinetics of presently available hypnotic drugs 9. Non-pharmacological treatment of an insomnia disorder 10. Benzodiazepine hypnotics 11. Zeta drugs : Zopiclone, Eszopiclone, Zolpidem, and Zaleplon 12. Melatonin and melatonin receptor agonists (Ramelteon, Tasimelteon) 13. Histamine H1 receptor antagonists (with special emphasis on low-dose Doxepin) 14. Orexin receptor antagonists (Suvorexant, Lemborexant) 15. Insomnia and CAM therapies: an evidence-based approach

Jaime M. Monti is Professor, Department of Pharmacology and Therapeutics, School of Medicine, Clinics Hospital, University of the Republic, Uruguay. He is a member of the International College of Neuropsychopharmacology, Sleep Research Society (USA), European Sleep Research Society, and the Argentinian Society of Sleep Medicine. S.R. Pandi-Perumal, M.Sc, is the President and Chief Executive Officer of Somnogen Canada Inc, a Canadian Corporation. He is a well-recognized sleep researcher both nationally and internationally, and has authored many publications. He has edited over 20 volumes related to sleep and biological rhythms research and he serves as Editor-in-Chief for Progress in Sleep Research. His general area of research interest includes sleep and biological rhythms.