This detailed book explores the interactions between different types of cells and immune cells, focusing on how their functionality is affected by immunosenescence. Beginning with traditional approaches, such as quantifying TRECs and measuring telomere lengths, the book continues with chapters on characterization of immune cell populations in aging, immune cell signaling, transcription factors, gene expression profiles, and the production of soluble factors such as cytokines, as well as computational approaches and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Immunosenescence: Methods and Protocols serves as an ideal guide for researchers working in this vital area of immunology and cell biology.
Edited by:
Roberta Amoriello, Clara Ballerini, Alice Mariottini Imprint: Springer-Verlag New York Inc. Country of Publication: United States [Currently unable to ship to USA: see Shipping Info] Edition: 2025 ed. Volume: 2857 Dimensions:
Height: 254mm,
Width: 178mm,
ISBN:9781071641279 ISBN 10: 1071641271 Series:Methods in Molecular Biology Pages: 230 Publication Date:01 October 2024 Audience:
Professional and scholarly
,
Undergraduate
Format:Hardback Publisher's Status: Active