The early chapters of the book provide a broad overview of the immune system and its functioning. The subsequent chapters present the importance of discriminating self from non-self through pattern recognition receptors (PRRs), structure and function of antibodies, major histocompatability complex, antigen receptors of the adaptive immune system, cellular interactions that lead to activation of T and B lymphocytes, immune responses against various categories of pathogens, and manipulation of the immune system by vaccination and various vaccine strategies. The book also includes clinically significant areas and hypersensitivity states including allergy, immunodeficiency disorders, transplantation and tumor immunology. There is also a special emphasis om the HIV/AIDS pandemic against which efforts are on at a massive scale. Tolerance and autoimmunity have also been linked for a better understanding of the mechanisms that could lead to autoimmune diseases.
An additional feature of the book is the inclusion of various techniques, immunoassays, and experimental systems provided in the appendix. ELISA and other immunological techniques like agglutination and precipitation having wide ranging applications have also been included in the book.
By:
Raj Khanna (Retired Professor University of Lucknow) Imprint: OUP India Dimensions:
Height: 244mm,
Width: 182mm,
Spine: 21mm
Weight: 636g ISBN:9780198068266 ISBN 10: 0198068263 Pages: 464 Publication Date:20 March 2011 Audience:
College/higher education
,
Professional and scholarly
,
Further / Higher Education
,
Undergraduate
Format:Paperback Publisher's Status: Active
1: The immune system - an introduction; 2: Innate immune response to infections; 3: The lymphoid system and cells of adaptive immunity; 4: Antigens and antibodies; 5: Major histocompatability complex (MHC); 6: Generation of antibody diversity and B lymphocyte development; 7: Cytokines; 8: T lymphocyte maturation and activation; 9: Effector mechanisms of cell-mediated immunity; 10: Activation of B lymphocytes; 11: Effector mechanisms of humoral immunity; 12: Immune response against microbes; 13: Vaccination and vaccine strategies; 14: Hypersensitivity reactions; 15: Immunologic tolerance and autoimmunity; 16: Immunodeficiency diseases; 17: Transplantation and graft rejection; 18: Tumor immunology; Appendix A Immunological techniques: principles and application; Appendix B Cumulative glossary