This volume focuses on IgG4-related disease (IgG4-RD), a novel clinical entity involving multiple organs and of unknown origin, associated with the abundant infiltration of IgG4-positive cells. It consists of nine chapters written by prominent experts in the field and discusses the disease concept, diagnosis and treatment, as well as recent findings on its pathogenesis and pathophysiology. As such, it offers an invaluable source of information for researchers and clinicians alike.
Edited by:
Kazuichi Okazaki Imprint: Springer International Publishing AG Country of Publication: Switzerland Edition: Softcover Reprint of the Original 1st 2017 ed. Volume: 401 Dimensions:
Height: 235mm,
Width: 155mm,
Weight: 2.175kg ISBN:9783319849300 ISBN 10: 3319849301 Series:Current Topics in Microbiology and Immunology Pages: 128 Publication Date:18 July 2018 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active
Current concept of IgG4-related disease.- Diagnosis and treatment of IgG4-related disease.- Immunogenetics of IgG4-related disease.- The histopathology of IgG4-related disease.- The immunobiology of immunoglobulin G-4 and Complement activation pathways in IgG4-related disease.- Th1/Th2 immune balance in IgG4-related disease.- Roles of plasmablasts and B cells in IgG4-related disease.- Roles of regulatory T and B cells in IgG4-related disease.- Roles of innate immunity in IgG4-related disease.
Kazuichi Okazaki, M.D. is chairman and professor of the Third Dept. of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University, Osaka, Japan