ICRP Publication 131: Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection...

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ICRP

ICRP Publication 131

Stem Cell Biology with Respect to Carcinogenesis Aspects of Radiological Protection

ICRP

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English

Sage Publications Ltd
25 December 2015

Ultrasonics; Radiology; Cellular biology (cytology)

Series: Annals of the ICRP

Summary
Details

This report provides a review of stem cells/progenitor cells and their responses to ionising radiation in relation to issues relevant to stochastic effects of radiation which form a major part of the ICRP system of radiological protection. Current information on stem cell characteristics, maintenance and renewal, evolution with age, location in stem cell ""niches"", radiosensitivity to acute and protracted exposures, is presented in a series of substantial reviews as Annexes concerning haematopoietic tissue, mammary gland, thyroid, digestive tract, lung, skin and bone. This foundation of knowledge of stem cells is used in the main text of the report to provide a biological insight to issues such as the linear-no-threshold (LNT) model, cancer risk among tissues, dose-rate effects and changes in the risk of radiation carcinogenesis by age at exposure and attained age.

Edited by: ICRP
Imprint: Sage Publications Ltd
Country of Publication: United Kingdom
Edition: 1
Dimensions: Height: 239mm, Width: 165mm, Spine: 15mm
Weight: 680g
ISBN: 9781473952065
ISBN 10: 1473952069
Series: Annals of the ICRP
Pages: 360
Publication Date: 25 December 2015
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active