Deepak Joshi, PhD, FRCP is a Consultant Hepatologist at the Institute of Liver Studies, King’s College Hospital, London, UK and a Reader in Hepatology at King’s College London, UK. Margaret G. Keane is an Assistant Professor at Johns Hopkins Hospital, Baltimore, USA. Jeremy Nayagam is a Consultant Hepatologist at the Institute of Liver Studies, King’s College Hospital, London, UK.