Handbook of Pharmaceutical Granulation Technology

Dilip M. Parikh (Synthon Pharmaceuticals, Inc., Ellicott City, Maryland, USA)

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English

CRC Press
29 January 2024

Medicine: general issues; Dermatology; Pharmacology; Biology, life sciences; Pharmaceutical technology

Series: Drugs and the Pharmaceutical Sciences

This fully revised edition of Handbook of Pharmaceutical Granulation Technology covers the rapid advances in the science of agglomeration, process control, process modelling, scale-up, emerging particle engineering technologies, along with current regulatory changes presented by some of the prominent scientist and subject matter experts around the globe. Learn from more than 50 global subject matter experts who share their years of experience in areas ranging from drug delivery and pharmaceutical technology to advances in nanotechnology. Every pharmaceutical scientist should own a copy of this fourth edition resource.

Key Features:

Theoretical discussions covering granulation and engineering perspectives. Covers new advances in expert systems, process modelling and bioavailability Chapters on emerging technologies in particle engineering Updated Current research and developments in granulation technologies

Edited by: Dilip M. Parikh (Synthon Pharmaceuticals Inc. Ellicott City Maryland USA)
Imprint: CRC Press
Country of Publication: United Kingdom
Edition: 4th edition
Dimensions: Height: 254mm, Width: 178mm,
Weight: 1.670kg
ISBN: 9780367741457
ISBN 10: 0367741458
Series: Drugs and the Pharmaceutical Sciences
Pages: 886
Publication Date: 29 January 2024
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

1 Introduction 2 Theory of Granulation: An Engineering Perspective 3 Drug Substance and Excipient Characterization 4 Binders in Pharmaceutical Granulation 5 Excipients and their Attributes in Granulation 6 Spray Drying and Pharmaceutical Applications 7 Emerging Technologies for Particle Engineering 8 Roller Compaction Technology 9 Advances in Wet Granulation of Modern Drugs 10 Fluid Bed Granulation 11 Single Pot Processing 12 Extrusion/Spheronization as a Granulation Technique 13 Continuous Granulation 14 Effervescent Granulation 15 Granulation of Plant Products and Nutraceuticals 16 Granulation Approaches for Modified Release Products 17 Granulation of Poorly Water-Soluble Drugs 18 Granulation and Production Approaches of Orally Disintegrating Tablets 19 Melt Granulation 20 Sizing of Granulation 21 Granulation Characterization 22 Bioavailability and Granule Properties 23 Granulation Process Modeling 24 Scale-Up Considerations in Granulation 25 Advances in Process Controls and End-Point Determination 26 Use of Artificial Intelligence and Expert Systems in Pharmaceutical Applications 27 Regulatory Issues in Granulation: Leading Next Generation Manufacturing

Dilip M. Parikh is President, DPharma Group Inc., Ellicott City, Maryland, USA. As a Chemical and pharmaceutical engineer, he has more than 45 years of experience in product developments and manufacturing, process engineering, operational management of various pharmaceutical facilities in Canada and the USA. He is an invited speaker globally on various solid dosage manufacturing technologies and troubleshooting, process optimization strategies, regulatory remediation, and PAT & QbD implementation strategies. The author of many scientific journal articles, book chapters, and the editor of first, the second and third edition of Handbook of Pharmaceutical Granulation Technology.