GnRH

Name: GnRH
Price: 392.41 AUD
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ISBN: 9780792376811

The Master Molecule of Reproduction

Andrea C. Gore

$490.95 $392.41

Hardback

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English

Kluwer Academic Publishers
30 April 2002

Endocrinology; Neurosciences; Animal reproduction

Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence. This text aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells. It should provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, the book takes a multi-species approach which should be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).

By: Andrea C. Gore
Imprint: Kluwer Academic Publishers
Country of Publication: United States
Edition: 2002 ed.
Dimensions: Height: 235mm, Width: 155mm, Spine: 20mm
Weight: 1.490kg
ISBN: 9780792376811
ISBN 10: 0792376811
Pages: 324
Publication Date: 30 April 2002
Audience: College/higher education , Professional and scholarly , Professional & Vocational , A / AS level , Further / Higher Education
Format: Hardback
Publisher's Status: Active

1. Neuroanatomy of the GnRH-1 System.- 2. GnRH Pulsatility.- 3. GnRH Neurons: Changes Across the Life Cycle.- 4. Factors Regulating GnRH Neurons.- 5. the GnRH Gene.- 6. Multiple GnRH Molecules, Phylogeny And Evolution.- 7. GnRH Neurons And Reproductive Behavior.- 8. GnRH Neuronal Cell Lines.- 9. GnRH Mutants And Transgenic Mice.- 10. GnRH in Humans.

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GnRH

The Master Molecule of Reproduction

Andrea C. Gore

$490.95 $392.41

Hardback

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