bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, ""Bitter sweetness of complexity,"" the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on ?(1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its ""guest,"" as well as the biological consequences resulting from this mutual interplay.
Edited by:
Thisbe K. Lindhorst,
Stefan Oscarson
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Publication: Germany
Edition: 2009 ed.
Volume: 288
Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 18mm
Weight: 508g
ISBN: 9783642013034
ISBN 10: 3642013031
Series: Topics in Current Chemistry
Pages: 186
Publication Date: 26 June 2009
Audience:
Professional and scholarly
,
Undergraduate
Format: Hardback
Publisher's Status: Active
Bitter Sweetness of Complexity.- Carbohydrate Receptors of Bacterial Adhesins: Implications and Reflections.- Structure, Function, and Assembly of Type 1 Fimbriae.- The Multiple Carbohydrate Binding Specificities of Helicobacter pylori.- Ins and Outs of Microbial Adhesion.- Staphylococcus epidermidis Biofilms: Functional Molecules, Relation to Virulence, and Vaccine Potential.- Architectures of Multivalent Glycomimetics for Probing Carbohydrate–Lectin Interactions.
Reviews for Glycoscience and Microbial Adhesion
?The sixth edition of this directory features information on some 1,300 current funding programs, organized by state, that offer support for some or all general operating expenses of nonprofits and other institutions. Each entry includes the sponsor name and address, contact information, the sponsor's areas of interest, and -- when available -- fax numbers, e-mail addresses, Web page addresses, eligibility requirements and contact procedures, restrictions, and samples of previously awarded grants.?-Reference & Research Book News
