Glycobiology of the Nervous System

Cara-Lynne Schengrund, Robert K. Yu

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English

Springer International Publishing AG
19 October 2022

Neurology & clinical neurophysiology; Neurosciences

Series: Advances in Neurobiology

This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.

Edited by: Cara-Lynne Schengrund, Robert K. Yu
Imprint: Springer International Publishing AG
Country of Publication: Switzerland
Edition: Second Edition 2023
Volume: 29
Dimensions: Height: 235mm, Width: 155mm,
Weight: 934g
ISBN: 9783031123894
ISBN 10: 3031123891
Series: Advances in Neurobiology
Pages: 501
Publication Date: 19 October 2022
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Cara-Lynne Schengrund, PhD, is Professor Emeritus, Department of Biochemistry and Molecular Biology, Penn State University, Hershey, Pennsylvania Robert K. Yu, PhD, Med ScD, was Professor, Department of Neuroscience and Regenerative Medicine, and GRA Eminent Scholar in Molecular and Cellular Neurobiology, Medical College of Georgia at Augusta University, Augusta, Georgia