Glycans in Diseases and Therapeutics

Mauro S.G. Pavão

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English

Springer-Verlag Berlin and Heidelberg GmbH & Co. K
29 May 2013

Medical research; Cellular physiology; Cellular biology (cytology); Zoology & animal sciences

Series: Biology of Extracellular Matrix

Summary
Details

Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.

This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.

Edited by: Mauro S.G. Pavão
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Country of Publication: Germany
Edition: 2011 ed.
Dimensions: Height: 235mm, Width: 155mm, Spine: 11mm
Weight: 314g
ISBN: 9783642267949
ISBN 10: 3642267947
Series: Biology of Extracellular Matrix
Pages: 188
Publication Date: 29 May 2013
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active