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Germfree and Gnotobiotic Animal Models

Background and Applications

Bernard S. Wostmann

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Hardback

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English
CRC Press Inc
19 June 1996
The germfree animal is reared in the laboratory

to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an

animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.

By:  
Imprint:   CRC Press Inc
Country of Publication:   United States
Dimensions:   Height: 234mm,  Width: 156mm,  Spine: 17mm
Weight:   430g
ISBN:   9780849340086
ISBN 10:   084934008X
Pages:   202
Publication Date:  
Audience:   College/higher education ,  Professional and scholarly ,  Professional & Vocational ,  A / AS level ,  Further / Higher Education
Format:   Hardback
Publisher's Status:   Active
Introduction. Early Growth, Body Weight, Reproduction, and Life Span. Anatomy, Morphology, and Function of the Gastrointestinal System. Morphology and Physiology, Endocrinology and Biochemistry. Nutrition. The Chemically Defined Diet. Immunology, Including Radiobiology and Transplantation. Parasitology. Pathology Over the Life Span of the Germfree Rat and the Germfree Mouse. Applications: Past, Present, and Future. Part I. Applications: Past, Present, and Future. Part II. Use of the Gnotobiote in the Study of Disease. Applications: Past, Present, and Future. Part III. The Production of Monoclonal Antibodies and Conclusions. Index. NTI Copy/Back cover copy

Bernard S. Wostmann (University of Notre Dame) (Author)

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