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Germ Cell Development in C. elegans

Tim Schedl

$370.95   $296.98

Hardback

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English
Springer-Verlag New York Inc.
08 August 2012
Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life.  Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms.  Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition.  This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.
Edited by:  
Imprint:   Springer-Verlag New York Inc.
Country of Publication:   United States
Edition:   2013 ed.
Volume:   757
Dimensions:   Height: 235mm,  Width: 155mm,  Spine: 30mm
Weight:   828g
ISBN:   9781461440147
ISBN 10:   1461440149
Series:   Advances in Experimental Medicine and Biology
Pages:   432
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Hardback
Publisher's Status:   Active
Introduction to germ cell development in C. elegans.- Germ cell specification.- Sex determination in the C. elegans germline.- Stem cell proliferation versus meiotic fate decision in C. elegans.- Physiological control of germline development.- Meiotic development in C. elegans.- Spermatogenesis.- Translational control in the C. elegans germ line.- Germ cell apoptosis and DNA damage responses.- Control of Oocyte Growth and Meiotic Maturation in C. elegans.- Fertilization.- The oocyte-to-embryo transition.- Epigenetic Control of Germline Development.- Using Caenorhabditis to explore the evolution of the germ line.- Index.

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