Gene Therapy of Cancer

Methods and Protocols

Wolfgang Walther

$460.95 $368.48

Hardback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We then advise you accordingly. If the time taken to get any book is too long for you, you can let us know and we will cancel or adjust your order, and refund as required.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

Springer-Verlag New York Inc.
24 June 2022

Medical genetics; Oncology

Series: Methods in Molecular Biology

This third edition provides new and updated chapters on gene therapeutic strategies of cancer. Chapters guide readers through suicide and oncolytic gene therapy, gene replacement and gene suppression therapy, vector development and refinement, immunogene therapy, TCR and CAR engineering, tumor vaccination using DNA or RNA vaccines, and antitumoral immune stimulation at different levels. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge, Gene Therapy of Cancer: Methods and Protocols, Third Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.

Edited by: Wolfgang Walther
Imprint: Springer-Verlag New York Inc.
Country of Publication: United States
Edition: Third Edition 2022
Volume: 2521
Dimensions: Height: 254mm, Width: 178mm,
Weight: 867g
ISBN: 9781071624401
ISBN 10: 1071624407
Series: Methods in Molecular Biology
Pages: 342
Publication Date: 24 June 2022
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Brief Introduction to Current Cancer Gene Therapy.- Minicircles for CAR T Cell Production by Sleeping Beauty Transposition - A Technological Overview.- Generation of CAR-T Cells with Sleeping Beauty Transposon Gene Transfer.- Generation of Redirected Engineered Human Chimeric Antigen Receptor (CAR) T cells.- TCR- and CAR-engineering of Primary Human T cells.- TCR Gene Therapy for Cancer.- Gene Gun Her2/neu DNA Vaccination: Evaluation of Vaccine Efficacy in a Syngeneic Her2/neu Mouse Tumor Model.- Construction of Minicircle Suicide Genes Coding for Ribosome-Inactivating Proteins.- Claudin-targeted Suicide Gene Therapy for Claudin-Overexpressing Tumor Cells by Using Modified Clostridium Perfringens Enterotoxin (CPE).- Bioengineered RNA Therapy in Patient-Derived Organoids and Xenograft Mouse Models.- Application of Transcription Factor Decoy Oligodeoxynucleotides (ODNs) for Cancer Therapy.- NK Cell Effector Functions and Bystander Tumor Cell Killing in Immunovirotherapy.- A qPCR-based Method for Quantification of Replication Competent Adenovirus (RCA) in Conditionally Replicating Oncolytic Adenoviruses.- Visualized Cancer Immunotherapy with Engineered Salmonella typhimurium.- CANCER Gene Therapy: Development and Production Of Lentiviral Vectors For Gene Therapy.- Capillary Gel Electrophoresis (CGE) for Quality Control of Plasmid DNA in Gene Therapy: quality control of 20-years stored GMP-grade Plasmid DNA.- Efficient Generation of Superior Dumbbell-Shaped Non-viral DNA Delivery Vectors Using 1-2-3 Gap-primer PCR.