Advanced Texts is a new programme of books published by BIOS, for advanced undergraduates and postgraduates. The books are short concise texts covering advanced topics typically studied in the final year of an undergraduate course or during taught-postgraduate courses. Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans. It looks at the functional role of glycoconjugate compounds in normal cellular processes, in both disease and development. The book also describes how these compounds can be studied, analysed and manipulated for use in biotechnology. Functional and Molecular Glycobiology is a unique introduction to the field bridging the gap between introductory books and current research.
Ch 1. An introduction to carbohydrate chemistry. Ch 2. Enzymes of glycosylation - the glycosyltransferases. Ch 3. Polysaccharides. Ch 4. N-linked glycoproteins. Ch 5. O-linked (mucin-type) glycoproteins. Ch 6. O-glcnac glycosylation of nuclear and cytosolic proteins. Ch 7. Species specific and unusual types of glycoprotein glycosylation. Ch 8. Glycoconjugates of the extracellular matrix of animals. Ch 9. Glycosphingolipids. Ch 10. Glycan chain extension and some common and important glycan structures. Ch 11. Sialic acids. Ch 12. Glycosylphosphatidylinositol (gpi)-anchored proteins. Ch 13. Carbohydrate-binding proteins (lectins). Ch 14. Tools for carbohydrate analysis. Ch 15. Modulation of glycan expression using inhibitors of N- and O-linked glycoconjugate processing, and transgenic technology. Ch 16. Disease processes in which carbohydrates are involved. Ch 17. Carbohydrate-based therapeutics. Ch18. Carbohydrate biotechnology.
Dr SusanBrooks, Dr M Dwek, Udo Schumacher
Reviews for Functional and Molecular Glycobiology
Direct and personable, Waddell's character comes through in this engaging depiction of the hunting world. -- Booklist