From Bench to Market: The Evolution of Chemical Synthesis

— —

Walter Cabri (R&D Director, Antibioticos, Rodano) Romano Di Fabio (Head of CNS Medicinal Chemistry, Glaxo-Wellcome)

From Bench to Market

Name: From Bench to Market
Price: 202 AUD
Availability: OutOfStock
ISBN: 9780198503835

The Evolution of Chemical Synthesis

Walter Cabri (R&D Director, Antibioticos, Rodano), Romano Di Fabio (Head of CNS Medicinal Chemistry, Glaxo-Wellcome)

$202

Paperback

Not in-store but you can order this
How long will it take?

Availability Information

We source books from suppliers in Australia and overseas. For books we don't currently have in stock, the time it takes to get them from our suppliers can vary widely - from a few days to a few months - so we check each book with each supplier to determine the expected time it will take to be supplied to us.

We will update you on expected arrival time to us. If this delay is too long, please let us know within 2 business days and we can give you options regarding cancelling or adjusting your order. More details on cancelling your order can be found in our Terms of Trade.

To find out the anticipated arrival time for specific items prior to ordering, please contact us by phone or email:

Phone +61 2 9264 3111, or 1800 4 BOOKS (1800 4 26657) if outside Sydney:
option 1 Abbey's Bookshop (Crime, History, Science, Kids & more) • info@abbeys.com.au
option 2 Language Book Centre (ESL & Foreign Languages) • language@abbeys.com.au
option 3 Galaxy Bookshop (Sci-fi, Fantasy, Romance, Graphic Novels) • sf@galaxybooks.com.au

QTY:

English

Oxford University Press
01 January 2001

Pharmaceutical industries; Pharmacology; Pharmaceutical technology

Who wins the race to turn molecules into medicines? How much does it cost? What factors influence the choice of synthetic routes and reaction mechanisms? How can pharmaceutical companies protect their discoveries? In From Bench to Market, Walter Cabri and Romano Di Fabio chart the process of industrial chemical synthesis, from the first discovery of a molecule, or 'new chemical entity', to its entry in the marketplace as a drug. They discuss all aspects related to the process research for bulk production, including comparison between different synthetic routes, key methodologies and reaction mechanisms, costs, patent competition, and crystalline forms. The authors use the real chemical history of the development of drugs from several therapeutic areas as detailed case studies, each chosen to illustrate a range of issues and methodologies in industrial chemistry. Several chapters cover the development of the various ß-lactam antibiotics; two chapters describe the discovery and synthesis of the anticancer drugs Idarubicin and Paclitaxal; in another chapter, the synthesis of the anti-viral drug Acyclovir and the 'patent war' that resulted are explored. Between them, the authors represent considerable first-hand experience in pharmaceutical research and development. The technical, practical, and strategic information they have amassed make this essential reading for graduate and undergraduate chemists intending to work in the pharmaceutical industry, as well as for industrial chemists themselves. Lecturers teaching courses in medicinal and organic chemistry will also find it useful.

By: Walter Cabri (R&D Director Antibioticos Rodano), Romano Di Fabio (Head of CNS Medicinal Chemistry, Glaxo-Wellcome)
Imprint: Oxford University Press
Country of Publication: United Kingdom
Dimensions: Height: 246mm, Width: 189mm, Spine: 16mm
Weight: 534g
ISBN: 9780198503835
ISBN 10: 0198503830
Pages: 284
Publication Date: 01 January 2001
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Walter Cabri, R+D Director, Research and Development, Antibioticos, Rodano, Italy wcabri@antibioticos.it Romano Di Fabio, Head of CNS Medicinal Chemistry, Medicines and Research Centre, Glaxo- Wellcome, Verona, Italy rdf26781@glaxowellcome.co.uk

Reviews for From Bench to Market: The Evolution of Chemical Synthesis

a unique book ... I highly recommendthis book to process chemists not only in the pharmaceutical industry but in the fine chemical, agrochemical, and colour chemical industries, too ... It is refreshing to see the book in paperback at a low cost. Highly recommended- I will certainly use it as a teaching aid Chemistry in Britain