Ferroptosis

Mechanism and Diseases

Andrés F. Florez, Hamed Alborzinia

$326.95 $261.21

Paperback

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English

Springer Nature Switzerland AG
11 August 2022

Medical research; Medical genetics; Lipids; Cellular biology (cytology)

Series: Advances in Experimental Medicine and Biology

This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron metabolism and its connection to ferritinophagy, a ferritin selective autophagy, with profound implications in neurodegenerative diseases such as Alzheimer, Parkinson, Huntington and ALS. Lastly, it describes necroptosis, another important form of cell death, along with its connections to human disorders and potential crosstalk with ferroptosis.

While covering basic concepts, the book delvesinto mechanisms and modulation of ferroptosis for treating a wide variety of human diseases thus offering a valuable and informative resource for both, scientists and clinical researchers.

Edited by: Andrés F. Florez, Hamed Alborzinia
Imprint: Springer Nature Switzerland AG
Country of Publication: Switzerland
Edition: 1st ed. 2021
Volume: 1301
Dimensions: Height: 254mm, Width: 178mm,
Weight: 303g
ISBN: 9783030620288
ISBN 10: 303062028X
Series: Advances in Experimental Medicine and Biology
Pages: 140
Publication Date: 11 August 2022
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Dr. Andrés F. Flórez is currently a Postdoctoral Fellow in the Department of Molecular and Cellular Biology (MCB) at Harvard University. His research is focused in understanding the oncogene-based mechanisms regulating ferroptosis and to use this knowledge for designing new therapeutic strategies. He is also interested in the role of ferroptosis in controlling bacterial cell populations. Dr. Hamed Alborzinia is a Postdoctoral Fellow in the Division of Stem Cells and Cancer at the German Cancer Research Center (DKFZ). He also belongs to the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM) in Heidelberg, Germany. His main research focus is to understand the metabolic properties of cancer cells in connection to novel forms of cell death, including ferroptosis.

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Ferroptosis

Mechanism and Diseases

Andrés F. Florez, Hamed Alborzinia

$326.95 $261.21

Paperback

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