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Evolutionary Bioinformatics

Donald R. Forsdyke

$399.95   $320.22

Paperback

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English
Springer International Publishing AG
27 May 2018
"Now in its third edition and

supplemented with more online material, this book aims to make the

""new"" information-based (rather than gene-based) bioinformatics

intelligible

both to the ""bio"" people and the ""info"" people. Books on bioinformatics

have traditionally served gene-hunters, and biologists who wish to

construct family trees showing tidy lines of descent. While dealing

extensively with the exciting topics of gene discovery

and database-searching, such books have hardly considered genomes as

information channels through which multiple forms and levels of

information have passed through the generations. This “new

bioinformatics” contrasts with the ""old"" gene-based bioinformatics

that so preoccupies previous texts. Forms of information that we are

familiar with (mental, textual) are related to forms with which we are

less familiar (hereditary). The book extends a line of evolutionary

thought that leads from the nineteenth century (Darwin,

Butler, Romanes, Bateson), through the twentieth (Goldschmidt, White),

and into the twenty first (the final works of the late Stephen Jay

Gould). Long an area of controversy, diverging views may now be

reconciled."

By:  
Imprint:   Springer International Publishing AG
Country of Publication:   Switzerland
Edition:   Softcover reprint of the original 3rd ed. 2016
Dimensions:   Height: 235mm,  Width: 155mm,  Spine: 26mm
Weight:   7.606kg
ISBN:   9783319804163
ISBN 10:   3319804162
Pages:   471
Publication Date:  
Audience:   Professional and scholarly ,  Undergraduate
Format:   Paperback
Publisher's Status:   Active
Part 1. Information and DNA.- 1. Memory – A Phenomenon of Arrangement.- 2. Chargaff’s First Parity Rule.- 3. Information Levels and Barriers.- Part 2. Parity and Non-Parity.- 4. Chargaff’s Second Parity Rule.- 5. Stems and Loops.- 6. Chargaff’s Cluster Rule.- Part 3. Variation and Speciation.- 7. Mutation.- 8. Species Survival and Arrival.- 9. The Weak Point.- 10. Chargaff’s GC Rule.- 11. Homostability.- Part 4. Conflict within Genomes.- 12. Conflict Resolution.- 13. Exons and Introns.- 14. Complexity.- Part 5. Conflict between Genomes.- 15. Self/Not-Self?.- 16. The Crowded Cytosol.- Part 6. Sex and Error-Correction.- 17. Rebooting the Genome.- 18. The Fifth Letter.- Part 7. Information and Mind.- 19. Memory – What is Arranged and Where?.- 20.Certainty Now Uncertain.

Donald Forsdyke graduated from St. Mary's Hospital, London University, UK in 1961. After house appointments at St.Mary's (Medical Unit and Department of Psychiatry) and the Addenbrooke's Hospital, Cambridge (Surgery), he began research in Molecular Biology and Cellular Immunology at the Department of Biochemistry, Cambridge (Ph.D. 1967). He was appointed to what was then the Department of Biochemistry at Queen's University in 1968. In 2013 he became President of the John Austin Society for the History of Medicine and Science.

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