Environmental Epigenetics in Toxicology and Public Health

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Rebecca Fry Trygve Tollefsbol (Professor of Biology, Senior Scientist, Comprehensive Cancer Center, Comprehensive Center for Healthy Aging, University of Alabama at Birmingham, AL, USA)

Environmental Epigenetics in Toxicology and Public Health

Rebecca Fry, Trygve Tollefsbol (Professor of Biology, Senior Scientist, Comprehensive Cancer Center, Comprehensive Center for Healthy Aging, University of Alabama at Birmingham, AL, USA)

$350.95

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English

Academic Press Inc
21 October 2020

DNA & Genome

Series: Translational Epigenetics

Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects.

This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures.

Edited by: Rebecca Fry
Series edited by: Trygve Tollefsbol (Professor of Biology Senior Scientist Comprehensive Cancer Center Comprehensive Center for Healthy Aging University of Alabama at Birmingham AL USA)
Imprint: Academic Press Inc
Country of Publication: United States
Dimensions: Height: 235mm, Width: 191mm,
ISBN: 9780128199688
ISBN 10: 0128199687
Series: Translational Epigenetics
Pages: 400
Publication Date: 21 October 2020
Audience: Professional and scholarly , Undergraduate
Format: Paperback
Publisher's Status: Active

Section I. Epigenetic Mechanisms/Machinery 1. DNA methylation/chromatic regulation/non-coding RNAs 2. Tools for the assessment of epigenetic regulation Section II. Transdisciplinary approaches for the study of environmental epigenetics 3. Model organisms and their application in environmental epigenetics 4. Epidemiological concepts in environmental epigenetics Section III. Epigenetic programming of disease in relation to the environment 5. Pregnancy and Birth outcomes 6. Neurodevelopment outcomes 7. Cancer 8. Respiratory dysfunction 9. Immune dysfunction 10. Cardio/Metabolic disease 11. Aging Section IV. Transgenerational epigenetic effects of the environment 12. Transgenerational effects of environmental contaminants Section V. Epigenome-targeted therapies in environmental health science 13. Nutrition 14. Manipulation of Epigenetic machinery Section VI. Conclusions and Future Perspectives 15. Conclusions and Future Perspectives: The environment and the epigenome

Trygve Tollefsbol is a Professor of Biology and a Senior Scientist in the Comprehensive Center for Healthy Aging, the Comprehensive Cancer Center, the Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999. Dr. Tollefsbol has doctorate degrees in molecular biology and osteopathic medicine and has edited and co-authored numerous books on the topics of epigenetics, cancer and aging and is Series Editor of Translational Epigenetics. Dr. Tollefsbol is a Professor of Biology and a Senior Scientist in the Center for Aging, Comprehensive Cancer Center, Nutrition Obesity Research Center, and the Comprehensive Diabetes Center at the University of Alabama at Birmingham (UAB). He is Director of the UAB Cell Senescence Culture Facility which he established in 1999 and a Steering Committee Member of the UAB Center for Aging.

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Environmental Epigenetics in Toxicology and Public Health

Rebecca Fry, Trygve Tollefsbol (Professor of Biology, <br>Senior Scientist, Comprehensive Cancer Center, Comprehensive Center for Healthy Aging, <br>University of Alabama at Birmingham, AL, USA)

$350.95

Paperback

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