Kathryn Klein graduated from the University of California, Irvine, with a BA degree in studio arts. She was first employed at the J. Paul Getty Museum as a preparator in 1986, and from 1988 to 1991 served as a conservation assistant in the museum's Decorative Arts and Sculpture Conservation department. At the University of New Mexico, Albuquerque, she completed her MA and PhD in Latin American studies, with areas of specialization in art history and anthropology and their application to art conservation. She has lived and traveled extensively in Mexico and Central America since 1980, and has served as a conservation consultant for the Getty Conservation Institute while working with various ethnographic collections at museums and weaving cooperatives in the Mexican states of Chiapas and Oaxaca.