This volume provides detailed methods and key approaches used to mechanistically study DNA damage, as well as the factors involved in the damage response. Chapters guide readers through proteomics and biophysical approaches, analyzing protein function, quantifying DNA replication dynamics and nucleic acid base damage, as well as biochemical reconstitution of key pathways involved in DNA repair. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, DNA Damage Responses: Methods and Protocols aims to be a useful practical guide to researches to help further their study in this field.
Edited by:
Nima Mosammaparast Imprint: Springer-Verlag New York Inc. Country of Publication: United States [Currently unable to ship to USA: see Shipping Info] Edition: 2022 ed. Volume: 2444 Dimensions:
Height: 254mm,
Width: 178mm,
Weight: 574g ISBN:9781071620656 ISBN 10: 1071620657 Series:Methods in Molecular Biology Pages: 284 Publication Date:16 March 2023 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active