Developmental Origins of Health and Disease

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Lucilla Poston (King's College London) Keith M. Godfrey (University of Southampton)

Developmental Origins of Health and Disease

Lucilla Poston (King's College London), Keith M. Godfrey (University of Southampton), Peter D. Gluckman (University of Auckland) , Mark A. Hanson (University of Southampton)

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English

Cambridge University Press
22 December 2022

Public health & preventive medicine; Reproductive medicine; Materno-fetal medicine; Paediatric medicine; Paediatric nursing

The concept of the early life developmental origins of health and disease (DOHaD) in adults has stimulated a new approach to understanding disease trajectories, with major public health implications. Indeed, the principle of the 'lifecourse of disease' now influences health policies internationally. Environmental influences during pregnancy and early life that affect lifelong health are well documented, but there is a new focus on the preconception period and the significance of paternal health on the fetus. This fully revised second edition highlights scientific and clinical advances in the field, exploring new understanding of mechanisms such as epigenetics and the increasingly recognised role of external influences, including pollution. The book is structured logically, covering environment, clinical outcomes, mechanisms of DOHaD, interventions throughout the lifespan and finally implications for public health and policy. Clinicians and scientists alike will improve their understanding of the developmental origins of health and disease with this essential text.

Edited by: Lucilla Poston (King's College London), Keith M. Godfrey (University of Southampton), Peter D. Gluckman (University of Auckland), Mark A. Hanson (University of Southampton)
Imprint: Cambridge University Press
Country of Publication: United Kingdom
Edition: 2nd Revised edition
Dimensions: Height: 261mm, Width: 183mm, Spine: 16mm
Weight: 650g
ISBN: 9781009272247
ISBN 10: 1009272241
Pages: 320
Publication Date: 22 December 2022
Audience: General/trade , ELT Advanced
Format: Hardback
Publisher's Status: Active

Lucilla Poston is Tommy's Charity Professor of Maternal and Fetal Health in the Department of Women and Children's Health and Head of the School of Life Course and Population Sciences at King's College London, UK. Keith M. Godfrey is Nutrition, Lifestyle and Metabolism Theme Lead in the National Institute for Health and Care Research Southampton Biomedical Research Centre. He is Professor of Epidemiology & Human Development at the University of Southampton and Director of the Centre for Developmental Origins of Health & Disease, UK. Peter D. Gluckman holds a Distinguished University Professorship at the Liggins Institute of the University of Auckland, Australia. Mark A. Hanson is Emeritus Professor of Human Development and Health and British Heart Foundation Professor at The University of Southampton, UK.