This work presents and evaluates methods employed to identify the potential of certain types of chemicals to adversely affect the skin. A variety of test methods are included such as tests for skin penetration, metabolism, irritation, the skin immune system, photo effects, skin cancer, and topical effects of retinoids and depigmenting chemicals. Tests for chemicals that affect the reproductive and nervous system are also included. Both animal and human tests that have been standardised and tests that are under development and employ animal alternatives are addressed in this book. Besides different testing methods, a rationale for accepting non-animal models and a review of some regulatory agency discussions about animal alternative tests are included.
Edited by:
Francis N. Marzulli (Consultant in Pharmacology Bethesda Maryland USA), Howard I. Maibach (University of California, USA.) Imprint: CRC Press Country of Publication: United Kingdom Dimensions:
Height: 229mm,
Width: 152mm,
Weight: 453g ISBN:9781138416789 ISBN 10: 1138416789 Pages: 412 Publication Date:18 December 2020 Audience:
Professional and scholarly
,
College/higher education
,
Undergraduate
,
Further / Higher Education
Format:Hardback Publisher's Status: Active