Cystic Fibrosis: Diagnosis and Protocols, Volume I: Approaches to Study and Correct CFTR Defects

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Margarida D. Amaral Karl Kunzelmann

Cystic Fibrosis

Diagnosis and Protocols, Volume I: Approaches to Study and Correct CFTR Defects

Margarida D. Amaral, Karl Kunzelmann

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English

Humana Press Inc.
25 May 2011

Medical laboratory testing & techniques; Cellular physiology; Medical genetics

Series: Methods in Molecular Biology

Despite the many milestones in cystic fibrosis (CF) research, progress towards curing the disease has been slow, and it is increasingly difficult to grasp and use the already wide and still growing range of diverse methods currently employed to study CF so as to understand it in its multidisciplinary nature. Cystic Fibrosis: Diagnosis and Protocols aims to provide the CF research community and related researchers with a very wide range of high-quality experimental tools, as an easy way to grasp and use classical and novel methods applied to cystic fibrosis. Volume I: Approaches to Study and Correct CFTR Defects focuses on the cystic fibrosis transmembrane conductance regulator (CFTR) and its expression, biogenesis, structure, and function in terms of the defects causing CF. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Comprehensive and practical, Cystic Fibrosis: Diagnosis and Protocols will provide readers with optimal working tools to address pressing questions in the best technical way, while helping all of us, as a research and clinical community, to move faster hand-in-hand toward unravelling the secrets of this challenging disorder and cure it.

Edited by: Margarida D. Amaral, Karl Kunzelmann
Imprint: Humana Press Inc.
Country of Publication: United States
Edition: 2011
Volume: 741
Dimensions: Height: 254mm, Width: 178mm, Spine: 36mm
Weight: 1.208kg
ISBN: 9781617791161
ISBN 10: 1617791164
Series: Methods in Molecular Biology
Pages: 528
Publication Date: 25 May 2011
Audience: Professional and scholarly , Undergraduate
Format: Hardback
Publisher's Status: Active

Reviews for Cystic Fibrosis: Diagnosis and Protocols, Volume I: Approaches to Study and Correct CFTR Defects

From the reviews: Summarize the current complex information on cystic fibrosis (CF) and the innovative new technologies available to basic scientists involved in the study of CF. ... This detailed book is aimed at basic research scientists and academicians working on CF. The protocols would be of use to graduate students and postdoctoral fellows as well. ... technology described would be invaluable to clinical laboratories involved in the diagnosis of CF. This represents a must-have guide for research laboratories working on the functional mechanisms of the CFTR gene. (Luis F. Escobar, Doody's Book Reviews, March, 2012)