This book covers the principles of cryopreservation as they relate the preservation of viable cells and cell materials being developed for biopharmaceutical applications. Topics include: the principles of freezing and thawing cells, physiochemical phenomena, process and system design options, method selection considerations, preservation procedures, cryoprotectant additives, freeze-drying human live virus vaccines, and transport system selection criteria. Contributions from well-known experts such as Steven S. Lee, Thomas
C. Pringle, William H. Siegel, Richard Wisniewski, and Fangdong Yin make this the single most important study available.
Edited by:
Kenneth E. Avis,
Carmen M. Wagner,
Carmen M. Wagner
Imprint: CRC Press Inc
Country of Publication: United States
Dimensions:
Height: 234mm,
Width: 156mm,
Spine: 38mm
Weight: 916g
ISBN: 9781574910902
ISBN 10: 1574910906
Pages: 504
Publication Date: 30 September 1999
Audience:
Professional and scholarly
,
College/higher education
,
General/trade
,
Undergraduate
,
Further / Higher Education
Format: Hardback
Publisher's Status: Active
Contents include: Principles & Scale-up: Cryopreservation for Cells, Microorganisms, Protein Solutions, Biopharmaceutical Formulations, & Biological Products. Large-Scale Cryopreservation: Process Development for Freezing & Thawing of Large Volumes of Cell Suspensions, Protein Solutions & Biological Products. Methods: Long-Term Preservation of Mammalian Cells & Microorganisms. Cryopreservation of Mammalian Cell Culture Materials. Freeze-Drying of Human Live Virus Vaccines. The Design & Use of Thermal Transport Containers.
Kenneth E. Avis , Carmen M. Wagner
