Inna Kuperstein is a researcher at Institut Curie, Paris, France, she is a coordinator of the Atlas of Cancer Signalling Networks (ACSN) project for construction and analysis of detailed signalling maps, development of tools and modelling the maps to predict drug response. She participates in multidisciplinary projects to decipher cell mechanisms rewiring in cancer. Emmanuel Barillot is the head of the Cancer and Genome: Bioinformatics, Biostatistics and Epidemiology of a Complex System department and scientific director of the bioinformatics platform at Institut Curie. His research focuses on methodological development and statistical analysis of high-throughput biological data and modeling with the aim to improve therapeutic treatments of cancer.