The most feared attribute of the human pathogen Vibrio cholerae is its ability to cause outbreaks that spread like wildfire, completely overwhelming public health systems and causing widespread suffering and death. This volume starts with a description of the contrasting patterns of outbreaks caused by the classical and El Tor biotypes of V. cholerae. Subsequent chapters examine cholera outbreaks in detail, including possible sources of infection and molecular epidemiology on three different continents, the emergence of new clones through the bactericidal selection process of lytic cholera phages, the circulation and transmission of clones of the pathogen during outbreaks and novel approaches to modeling cholera outbreaks. A further contribution deals with the application of the genomic sciences to trace the spread of cholera epidemics and how this information can be used to control cholera outbreaks. The book closes with an analysis of the potential use of killed oralcholera vaccines to stop the spread of cholera outbreaks.
Edited by:
G. Balakrish Nair, Yoshifumi Takeda Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Country of Publication: Germany Edition: Softcover reprint of the original 1st ed. 2014 Volume: 379 Dimensions:
Height: 235mm,
Width: 155mm,
Spine: 15mm
Weight: 4.219kg ISBN:9783662522714 ISBN 10: 3662522713 Series:Current Topics in Microbiology and Immunology Pages: 263 Publication Date:23 August 2016 Audience:
Professional and scholarly
,
Undergraduate
Format:Paperback Publisher's Status: Active