Cell Signaling

Interplay, Mechanisms, and Therapeutic Implications

Adeeb Shehzad

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Hardback

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English

CRC Press
16 April 2025

Immunology; Endocrinology; Biochemistry; Cellular biology (cytology)

This book provides a comprehensive understanding of cell signaling, molecular interactions, and their implications for human health and diseases. It introduces fundamental principles underlying cell communication through signaling molecules and their diverse transmission and reception mechanisms, highlighting their role in intercellular communication through voltage- and ion-gated channels, immunological and neuron synapses, and rhinovirus–receptor interaction involved in pathogenesis and disease development. Toward the end, the book highlights the profound implications of altered cell signaling pathways in the inflammation and immune response followed by the progression of various disorders, including cancer, endocrine disorders, and neurological illnesses. It explores the diagnostic and therapeutic implications of cell signaling in targeted therapies, highlighting advanced techniques for detecting signaling molecules and innovative therapeutic approaches to inspire new developments in precision medicine. It serves as an important resource for academics, students, and professionals in the fields of cell biology and biomedical sciences.

Key Features:

Provides in-depth understanding of cell signaling, exploring its complexities and impact on human health and disease Introduces fundamental principles of cell communication, emphasizing the different signaling molecules and their various transmission pathways Focuses on complex structures and functions of receptors, highlighting their essential role in intercellular communication and regulating cellular behavior Examines the molecular aspects of cell surface adhesion receptors, elucidating protein–protein interactions, signaling cascades, and enzyme–substrate interactions Discusses the impact of cell signaling on inflammation, cancer, and endocrine and neurological disorders

Edited by: Adeeb Shehzad
Imprint: CRC Press
Country of Publication: United Kingdom
Dimensions: Height: 254mm, Width: 178mm,
Weight: 950g
ISBN: 9781032707440
ISBN 10: 1032707445
Pages: 412
Publication Date: 16 April 2025
Audience: College/higher education , Professional and scholarly , Primary , Undergraduate
Format: Hardback
Publisher's Status: Active

Dr Adeeb Shehzad is currently Associate Professor at Biodiversity Unit, Research Center, Dhofar University, Oman and OIC of Lab of Biochemistry at Department of Biomedical Engineering and Sciences, SMME, NUST, Pakistan. He obtained his B.Pharmacy from the University of Peshawar, Pakistan in 2003. He completed his MS and Ph.D degree from Kyungpook National University, South Korea (2008–2014). He has published over 100 scientific publications and book chapters in refereed journals. Before joining NUST, Dr Adeeb has worked production pharmacist at Glaxo Smith Kline Pvt Ltd, Karachi, Pakistan and Medicraft Pharmaceutical Pvt Ltd, Peshawar, Pakistan from 2003-2007. His research interest is mainly oriented to the screening and development of plant isolated compounds as anticancer agents, as well as investigating the modulation of different signaling pathways in different types of cancers causing drug resistance and poor prognosis. Dr Adeeb is also interesting in development of kits for diagnosis and drug release patches with validation in animal models. Dr Adeeb is working as Editorial board member for several journals and has authored two books with international publishers. He received a number of national and international awards in academics and research.