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VOLUME I PART I. Extracorporeal Life Support Editorial Kaan Kirali Introduction: Surgical Perspective Marko Turina Introduction: Perfusional Perspective Gerard J. Myers PART II. Artificial Circulation and Respiration 1. Development of Extracorporeal Circulation Steven Tsui and Ismail Vokshi 2. Future Artificial Surface Physiology Manoj Myneni and Keshava Rajagopal 3. Future Artificial Heart O.H. Frazier 4. Future Artificial Lung Justyna Swol 5. Future Noninvasive Monitoring Silvia Mariani, Maria De Piero and Axel Haveric 6. 3D Printing for Artificial Physiology Zhonghua Sun 7. Advances for Artificial Circulation Guidelines Kaan Kirali PART III. Cardiopulmonary Bypass (CPB) 8. Basics of Extracorporeal Circulation Vipin Zamvar and Peter Lang 9. Pathophysiology of Cardiopulmonary Bypass Kaan Kirali, Davut Cekmecelioglu, Tanil OEzer, Tolga Bas and Hulya Yuk 10. Microcirculation During Cardiopulmonary Bypass Thanos Athanasiou, Maria Fergadi and Dimitrios Magouliotis 11. Standards for Cardiopulmonary Bypass David Fitzgerald and Justin Resley 12. Mechanical Pumps for Cardiopulmonary Bypass Georg Maximilian Wieselthaler 13. Oxygenators for Cardiopulmonary Bypass Korneel Vandewiele and Stefaan Bouchez 14. Cannulations for Cardiopulmonary Bypass Gino Gerosa, Assunta Fabozzo and Chiara Tessari 15. Anesthesia During Cardiopulmonary Bypass Antonio Pisano, Carolina Soledad Romero Garcia, Nicola Galdieri and Giovanni Landoni 16. Monitoring During Cardiopulmonary Bypass Kaan Kirali, Mustafa EMRE Gurcu, Pinar Karaca Baysal and OEzlem Oguzhan 17. Transesophageal Echocardiography During Cardiopulmonary Bypass Federico Pappalardo, Giulia Maj and Stephanie Bertolin 18. Hemostasis During Cardiopulmonary Bypass Giuseppe G. Faggian, Francesco Onorati, Ilaria Tropea, Annalisa Bernabei and Alessandra Francica 19. Myocardial Preservation During Cardiopulmonary Bypass Kaan Kirali, Hakan Hancer, Taylan Adademir, Tolga Bas and Mine Simsek 20. Cerebral Preservation During DHCA in Cardiopulmonary Bypass Shahzad G. Raja PART IV. Special Cardiopulmonary Bypass 21. Cardiopulmonary Bypass in Pregnancy Hartzell Schaff and Sri Harsha Patlolla 22. Cardiopulmonary Bypass in Neonates and Infants Akif Undar, Ryan M. Holcomb, Krishna Patel and Yongwook Dan 23. Cardiopulmonary Bypass in Pediatrics Afksendiyos Kalangos and Nataliia Shatelen 24. Cardiopulmonary Bypass in Thoracic Aortic Surgery Davut Cekmecelioglu, Kathleen Kibler, Vicente Orozco-Sevilla, and Joseph S. Coselli 25. Cardiopulmonary Bypass in Lung Transplantation Alexander Sasha Krupnick, Aakash Shah and Joshua L. Leibowitz 26. Cardiopulmonary Bypass in Non-Cardiac Thoracic Surgery Basar Sareyyupoglu, Magdy M. El-Sayed Ahmed and Mathew Thomas PART V. Special Situations for Perfusion 27. Perfusion Ethics, Accreditation and Education David Fitzgerald and David Fisher Jr 28. Perfusion Training Sven Maier and Christoph Benk 29. Perfusion Management Filip De Somer 30. Perfusion Accidents Management Carrel Thierry, Erich Gygax and Sarah Longnus-Henning 31. Perfusion Separation Challenge Vladimir Lomivorotov and Ludmila Lomivorotova 32. Perfusion for HIPEC Mustafa Duman, Erdal Polat, Mehmet Can, Kaan Kirali and Ercan Ersoy Part VI. Miniaturizing Cardiopulmonary Bypass 33. Miniaturizing Cardiopulmonary Bypass (MiCPB) Kyriakos Anastasiadis, Polychronis Antonitsis, Kyriakos Anastasiadis, Helena Argiriadou and Apostolos Deliopoulos 34. MiCPB in Cardiac Surgery Konstantinos S. Mylonas and Dimitrios V. Avgerinos 35. MiCPB in Heart Valve Surgery Kaan Kirali 36. MiCPB in Robotic Cardiac Surgery Michael J. Bates, W. Douglas Boyd, L. Wiley Nifong and Randolph Chitwood 37. MiCPB in Pediatrics Giovanni Battista Luciani, Alessio Rungatscher, Daniele Linardi and Stiljan Hoxha Part VII. Organ Injury and Protection in Cardiopulmonary Bypass 38. Metabolic Aspects in Cardiopulmonary Bypass John R. Cooper Jr, Katherine Gordon and Claudia Yu Yao Wei 39. Inflammatory Injury in Cardiopulmonary Bypass Shahzad G. Raja 40. Inflammatory Protection and Immune Support for Cardiopulmonary Bypass Shahzad G. Raja 41. Lung Injury in Cardiopulmonary Bypass Stephen C. Clark and Vikrant Pathania 42. Pulmonary Protection and Respiratory Support for Cardiopulmonary Bypass Kaan Kirali, Halide Ogus, Mustafa Mert OEzgur and Ugur Eke 43. Brain Injury in Cardiopulmonary Bypass Michael P. Vallely, Fabio Ramponi, Kaye Hon, Michael Seco, John D. Puskas, Jonathon Fanning, Stuart Grieve, Paul Bannon and Leonard Kritharides 44. Cerebral Protection and Neurologic Support John M. Murkin and Agya Boakye Atonsah Prempeh 45. Kidney Injury in Cardiopulmonary Bypass Eduard Quintana, Cristina Ibanez, Juan Perdomo, Alicia Molina-Andujar and Esteban Poch 46. Renal Protection and Nephritic Support for Cardiopulmonary Bypass Kaan Kirali, OEzge Altas, Mustafa Emre Gurcu and Sefika Kilic 47. Splanchnic Protection and Support for Cardiopulmonary Bypass Paulo Roberto Barbosa Evora, Gabriel Bianco Giuliani, Cecilio Jacob and Patricia Martinez 48. Intestinal Protection and Enteric Support for Cardiopulmonary Bypass Amer Harky, Kelly Wright and Naomi Melamed 49. Endocrinological Protection and Hormonal Support for Cardiopulmonary Bypass Paulo Roberto Barbosa Evora, Gabriel Bianco Giuliani, Cecilio Jacob and Patricia Martinez 50. Vessels Injury in Cardiopulmonary Bypass Assunta Fabozzo, Chiara Tessari, Giorgia Cibin and Gino Gerosa 51. Infectional Protection and Antimicrobial Support for Cardiopulmonary Bypass Kaan Kirali, Yesim Uygun Kizmaz, Pinar Atagun Guney and Nuray Cankaya VOLUME II Part VIII. Extra Corporeal Membranous Oxygenation (ECMO) 52. Extracorporeal Membrane Oxygenation (ECMO) Kaan Kirali, Atakan Erkilinc, Serpil Gezer Tas and Ismail Yerli 53. Contraindications for ECMO John Kyle Bohman, Misty Radosevich and Shihab Sugeir 54. Hemodynamic Evaluation of Cannulas for ECMO Akif Undar, Krishna Patel, David Palanzo, Christoph Brehm and John L. Myers 55. ECG-Synchronized Pulsatility for ECMO Akif Undar, Estelle Green, Orhun Davarci, Krishna Patel and Joseph B. Clark 56. Cardiac Protection and Management during ECMO Kaan Kirali, Deniz Gunay, Mehmet Aksut, Sabit Sarikaya and Haci Aslan 57. Pulmonary Protection and Management during ECMO Steven Keller 58. Hemorraghic Protection and Management during ECMO Hanne Berg Ravn and Henrik Schmidt 59. Cerebral Protection and Management during ECMO Mirko Belliato, Andrea Pellegrini and Roberto Veronesi Sr. 60. Renal Protection and Management during ECMO Kaan Kirali, Murat Gucun, Aytac Polat and Nazli Kilic 61. Gastrointestinal Protection and Management during ECMO Paulo Roberto Barbosa Evora, Cecilio Jacob, Gabriel Bianco Giuliani and Patricia Martinez 62. Vascular Protection and Management during ECMO Subhasis Chatterjee, Chibueze Onyemkpa, Zachary Pallister, Orlando Suero and Jayer Chung 63. Infection Protection and Management during ECMO Nicolo Patroniti and Angelo Insorsi 64. Inflammatory Protection and Management during ECMO Kiran Shekar, Elliott Theodrose Worku and Katrina K. Ki Part IX. Special Situations for ECMO 65. Ethics and Quality Assurance for ECMO Kollengode Ramanathan, Kiran Shekar and Ujwal Dhundi 66. Education and Training for ECMO Melissa Brunsvold, Robert E Bulander Jr and Ahmad Abutaka 67. Nursing Care for ECMO Jo-anne Fowles and Andrew Hadley-Brown 68. Transport and Retrieval for ECMO Ahmed Labib and Guillaume Alinier 69. Weaning Strategies for ECMO and Awake ECMO Wiebke Sommer and Gregor Warnecke Part X. ECMO Support in Non-Cardiac Etiology 70. ECMO in Neonates and Infants Denise Suttner 71. CRRT during ECMO in Neonates and Infants Akif Undar, Lilly Su, Ryan M. Holcomb and John L. Myers 72. ECMO in Nonsurgical Lung Conditions John Kyle Bohman, Juan Camilo Diaz Soto and Misty Radosevich 73. ECMO in Lung Surgery Shahrokh Taghavi, Alberto Benazzo, Konrad Hoetzenecker and Anders Andreasson 74. ECMO in Intracranial Surgery Gevalin Srisooksai and Christoph N. Seubert 75. ECC/ECMO in Controlled Reperfusion of Whole Body (CARL) Georg Trummer, Christoph Benk, Jan-Steffen Pooth, Sam Brixius and Friedhelm Beyersdorf 76. ECMO in Accidental Hypothermia Kiran Shekar, Saikat Mitra, Kollengode Ramanathan and Justyna Swol 77. ECMO in Trauma Akbarshakh Akhmerov and Danny Ramzy 78. ECMO in Pandemics Cara Agerstrand, Briana Short, Philippe H. Lemaitre and Meaghan Flatley 79. ECMO in COVID-ARDS Kaan Kirali, Adile Ece Altinay, Sirin Menekse and Sibel Aydin Part XI. ECMO Support in Non-Surgical Cardiac Etiology 80. ECMO for Challenging Percutaneous Intervention Matthew Acton, Corbin E. Goerlich and Ahmet Kilic, 81. ECMO for End-stage Heart Failure Ahmet Kilic, Corbin E. Goerlich and Matthew Acton 82. ECMO for Cardiogenic Shock Ibrahim Akin, Michael Behnes and Tobias Schupp 83. ECMO for Cardiopulmonary Arrest (E-CPR) Hanne Berg Ravn and Henrik Schmidt Part XII. ECMO Support in Surgical Cardiac Etiology 84. ECMO for Postcardiotomy Syndrome in Adults Alexis Edward Shafii and Bhalinder Dhaliwal 85. ECMO for Postcardiotomy Syndrome in Pediatrics Katsuhide Maeda and Tracey R. Geoffrion 86. ECMO for post-LVAD Right Ventricular Failure Jasmin Sarah Hanke, Gunes Dogan and Jan D. Schmitto 87. ECMO for Thoracic Transplantation Leslie James, Deane E. Smith and Nader Moazami Part XIII. Non-ECMO Artificial Life Support 88. Non-ECMO Artificial Circulatory Support Devices Mevlut Celik and Simon Maltais 89. Non-ECMO Artificial Respiratory Support Devices Jung-Yien Chien, Ting-Yu Liao and Yih-Sharng Chen 90. Non-ECMO Artificial Circulatory Support for Postcardiotomy Syndrome Kenneth K. Liao and Harveen Lamba 91. Non-ECMO Artificial Circulatory Support for Percutaneous Interventions Gregory W. Serrao, Anoop Ninan Koshy and Samin Sharma 92. Non-ECMO Artificial Life Support for Thoracic Transplantation Jae-Seung Jung and SeokJin Haam Epilogue Kaan Kirali
After finishing the Medicine Faculty of Istanbul University in 1990, Prof Kirali fulfilled MD, MSc medical mandatory service duty and began his residency training in Kosuyolu Heart and Research Hospital in 1992. Following 5 years of assistant education, he was in England and the USA for education and training in 1998. He performed his work mostly in the field of videoscopic and minimally invasive cardiac surgery, and he became a consultant cardiovascular surgeon in 1998, Assistance Professor in 1999, Associate Professor in 2002, and chief in 2005 at the same hospital. Over the last 20 years, he has focused his scientific interests on topics related to cardiovascular repairs requiring special experience. With his expertise in coronary artery surgery, minimal invasive cardiac surgery, valve repair, and aortic root surgery, he has established new methods for awake coronary bypass revascularization, new surgical approach for AVR during first and re-operations, aortic valve sparing procedure, and radiofrequency ablation. He is the pioneer of awake complete CABG with BIMA and has also developed a new aortotomy incision technique for all kinds of aortic valvular or subvalvular interventions during first and re-operations, which simplifies the procedure with/without aortic valve insertion. He has experience on cardiac failure during ECMO and developed a specific design for recovery. He has been the director of transplantation department since 2015. Prof. Joseph Coselli is the chief Professor of Surgery, of the Division of Cardiothoracic Surgery and the Executive vice-chair of Michael E. DeBakey Department of Surgery at Baylor College of Medicine, United States. He has specialized in the evaluation and treatment of aortic disease, including the aortic valve and root, the aortic arch, and the thoracoabdominal aorta, using open surgical and endovascular techniques. In 40 years of service, he has performed more than 10,500 aortic repairs, including more than 3700 repairs of thoracoabdominal aortic aneurysms, for which he is world-renowned. Prof Kalangos MD, PhD is a Greek-Swiss cardiovascular surgeon and Philanthropist. He currently serves as the Chairman of the Department of Pediatric and Congenital Cardiovascular Surgery at Mitera Hospital in Athens and as a full Professor of Pediatric Cardiovascular Surgery at Koc University Hospital in Istanbul, Turkiye. He is the President and founder of the Kalangos Foundation, the President and founder of the Global Forum on Humanitarian Medicine in Cardiology and Cardiac Surgery and the President and co- founder of Global Heart Network. He was the former President of the World Society of Cardiovascular and Thoracic Surgeons in 2014-2015 and is currently the treasurer of the society. He is also the inventor of the Kalangos biodegradable annuloplasty Rin. This device is being used in the repair of the mitral and tricuspid valves especially in children.
